Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601474 | 0.88 | TAAR1 (0.43) | TAAR1ALDH1A1TP53SIGMAR1TSHR | |
| SCHEMBL30629029 | 0.84 | TAAR1 (0.41) | TAAR1ALDH1A1TP53SIGMAR1ADRA2C | |
| SCHEMBL1954433 | 0.84 | TAAR1 (0.41) | TAAR1ALDH1A1TP53SIGMAR1ADRA2C | |
| SCHEMBL18773862 | 0.77 | ALDH1A1 (0.41) | TAAR1ALDH1A1TP53SIGMAR1CXCR4 | |
| SCHEMBL11557705 | 0.75 | MAPT (0.44) | ALDH1A1TP53SIGMAR1TSHRACHE | |
| SCHEMBL7186151 | 0.73 | CARM1 (0.42) | TAAR1ALDH1A1TP53SIGMAR1TSHR | |
| SCHEMBL29788888 | 0.73 | PIM1 (0.36) | TAAR1ALDH1A1TP53TSHR | |
| SCHEMBL6882345 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TP53TSHR | |
| SCHEMBL14940759 | 0.72 | MAOA (0.38) | CXCR4CARM1PRMT6PRMT8 | |
| SCHEMBL10693144 | 0.72 | DHFR (0.44) | ALDH1A1TP53SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114881-A1 | ANTI-NEOPLASTIC COMPOUNDS, COMPOSITIONS AND METHODS | PROGENRA INC. (US) | 2010-10-07 | — | — | WO | disclosed |