Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4434712 | 0.98 | CA1 (0.46) | CA1CA2POLBALDH1A1KMT2A | |
| SCHEMBL4532361 | 0.81 | HTT (0.35) | ALDH1A1SMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL4432705 | 0.81 | CA12 (0.46) | POLBTSHRMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4003537 | 0.75 | CA1 (0.41) | CA1CA2POLBALDH1A1KMT2A | |
| SCHEMBL28238995 | 0.75 | HSD11B1 (0.40) | POLBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL28504878 | 0.74 | NAMPT (0.31) | POLBALDH1A1 | |
| SCHEMBL28578134 | 0.74 | ALDH1A1 (0.33) | POLBALDH1A1KMT2AGAASMN1; SMN2 | |
| SCHEMBL29021543 | 0.72 | SMN1; SMN2 (0.33) | POLBALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL29021818 | 0.72 | — | — | |
| SCHEMBL29021475 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |