Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 16/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 15/20 | 0.58 |
| ▸ | TP53BP1 | Q12888 | 6/20 | 0.56 |
| ▸ | MBTD1 | Q05BQ5 | 6/20 | 0.56 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.53 |
| ▸ | L3MBTL4 | Q8NA19 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | PHF20 | Q9BVI0 | 1/20 | 0.51 |
| ▸ | MORF4L1 | Q9UBU8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2914468 | 0.74 | L3MBTL3 (0.65) | L3MBTL3L3MBTL1TP53BP1MBTD1L3MBTL4 | |
| SCHEMBL27537578 | 0.74 | MCL1 (0.73) | KMT2AMCL1CYP2C9 | |
| SCHEMBL1085344 | 0.72 | L3MBTL3 (0.72) | L3MBTL3L3MBTL1TP53BP1MBTD1L3MBTL4 | |
| SCHEMBL8163565 | 0.71 | L3MBTL3 (0.83) | L3MBTL3L3MBTL1TP53BP1MBTD1L3MBTL4 | |
| SCHEMBL1083716 | 0.70 | L3MBTL3 (0.58) | L3MBTL3L3MBTL1TP53BP1MBTD1L3MBTL4 | |
| SCHEMBL10293557 | 0.70 | L3MBTL3 (1.00) | L3MBTL3L3MBTL1TP53BP1MBTD1L3MBTL4 | |
| SCHEMBL3690932 | 0.70 | HRH3 (0.47) | L3MBTL3L3MBTL1MBTD1SMYD2 | |
| SCHEMBL4943334 | 0.70 | MCL1 (0.71) | MCL1 | |
| SCHEMBL1083720 | 0.69 | L3MBTL3 (0.53) | L3MBTL3L3MBTL1TP53BP1MBTD1L3MBTL4 | |
| SCHEMBL3399560 | 0.69 | HTR2C (0.62) | L3MBTL3L3MBTL1TP53BP1MBTD1SMYD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940786-A1 | BIPHENYL DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C | Arrow Therapeutics Limited (GB) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007031791-A1 | BIPHENYL DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C | ARROW THERAPEUTICS LIMITED (GB) | 2007-03-22 | — | — | WO | disclosed |