SCHEMBL2914468

SCHEMBL2914468

Cc1ccc(C(=O)N2CCC(N3CCCC3)CC2)cc1-c1ccc(C(=O)O)cc1

nearest known ligand 0.65

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL3 Q96JM7 19/20 0.65
▸ L3MBTL1 Q9Y468 16/20 0.65
▸ MBTD1 Q05BQ5 5/20 0.59
▸ TP53BP1 Q12888 2/20 0.59
▸ L3MBTL4 Q8NA19 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2906631 0.82 PLA2G7 (0.62) —
SCHEMBL21779417 0.78 MERTK (0.64) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL23682749 0.77 L3MBTL3 (1.00) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL20094151 0.77 L3MBTL3 (0.64) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL23682730 0.76 L3MBTL3 (1.00) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL8163565 0.76 L3MBTL3 (0.83) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL764630 0.76 L3MBTL3 (0.84) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL23682947 0.75 L3MBTL3 (1.00) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL12835045 0.74 L3MBTL3 (0.85) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL4601494 0.74 L3MBTL3 (0.58) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1940786-B1 BIPHENYL DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C ARROW THERAPEUTICS LTD (GB) 2010-08-18 — — EP disclosed
US-20080255105-A1 Biphenyl Derivatives and Their Use in Treating Hepatitis C ARROW THERAPEUTICS LIMITED (GB) 2008-10-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080255105-A1 Biphenyl Derivatives and Their Use in Treating Hepatitis C NR4A1, NR0B1, NR1H4 L3MBTL3 900/4885L3MBTL1 654/4885MBTD1 3893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback