SCHEMBL4601557

SCHEMBL4601557

CCCCC(CC)COc1ccccc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.58
ALDH1A1 P00352 7/20 0.52
CYP3A4 P08684 4/20 0.52
CA2 P00918 2/20 0.52
PRSS1 P07477 1/20 0.47
PRSS2 P07478 1/20 0.47
PRSS3 P35030 1/20 0.47
GAA P10253 2/20 0.44
JAK2 O60674 1/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 3/20 0.42
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
KDM4E B2RXH2 1/20 0.41
TSHR P16473 3/20 0.41
HSD17B10 Q99714 1/20 0.41
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30122823 1.00 LMNA (0.58) LMNAALDH1A1CYP3A4CA2PRSS1
SCHEMBL1777606 0.89 ALDH1A1 (0.55) LMNAALDH1A1CYP3A4CA2PRSS1
SCHEMBL9437435 0.88 PRSS1 (0.47) LMNAALDH1A1CYP3A4CA2PRSS1
SCHEMBL79322 0.87 GAA (0.53) LMNAALDH1A1CA2GAAJAK2
SCHEMBL22207433 0.87 LMNA (0.51) LMNAALDH1A1CYP3A4CA2PRSS1
SCHEMBL17912855 0.84 LMNA (0.51) LMNAALDH1A1CYP3A4CA2PRSS1
SCHEMBL12581112 0.83 CYP3A4 (0.50) LMNAALDH1A1CYP3A4CA2PRSS1
SCHEMBL13732601 0.82 CYP3A4 (0.49) LMNAALDH1A1CYP3A4CA2PRSS1
SCHEMBL30002958 0.82 ALDH1A1 (0.53) LMNAALDH1A1CYP3A4CA2PRSS1
SCHEMBL19612465 0.82 ALDH1A1 (0.53) LMNAALDH1A1CYP3A4CA2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115611748-B Separation method of 1, 5-pentanediamine 上海凯赛生物技术股份有限公司 2024-07-05 CN disclosed
CN-115611748-A Separation method of 1, 5-pentanediamine 上海凯赛生物技术股份有限公司 2023-01-17 CN disclosed
EP-1245405-B1 Image recording material FUJIFILM CORP (JP) 2008-04-23 EP disclosed
US-7252922-B2 Support having a rear surface and an image recording layer disposed on the support, and image recording layer having a front surface including, a radical generating onium salt, and a radically polymerizable compound FUJIFILM CORPORATION (JP) 2007-08-07 US disclosed
US-7196194-B2 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD (JP) 2007-03-27 US disclosed
US-20040122238-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD. 2004-06-24 US disclosed
US-20040096787-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD. 2004-05-20 US disclosed
US-6727053-B2 FORMS AN AZOMETHINE DYE UPON A COUPLING REACTION WITH AN OXIDIZED PRODUCT OF A DEVELOPING AGENT FUJI PHOTO FILM CO., LTD. (JP) 2004-04-27 US disclosed
US-20030073047-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJIFILM CORPORATION (JP) 2003-04-17 US disclosed
US-20030008228-A1 Support having a rear surface and an image recording layer disposed on the support, and image recording layer having a front surface including, a radical generating onium salt, and a radically polymerizable compound FUJIFILM CORPORATION (JP) 2003-01-09 US disclosed
EP-1245405-A2 Image recording material FUJI PHOTO FILM CO., LTD. (JP) 2002-10-02 EP disclosed
EP-1246006-A2 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD. (JP) 2002-10-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030073047-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound CBR1, IK, CBR3 LMNA 1880/4885ALDH1A1 377/4885CYP3A4 312/4885
US-20040122238-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound CBR1, CBR3, IK LMNA 1594/4885ALDH1A1 331/4885CYP3A4 421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.