Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601033 | 0.84 | EGFR (0.44) | EGFRTHRB | |
| SCHEMBL4600070 | 0.83 | EGFR (0.42) | EGFRSCN9A | |
| SCHEMBL4602061 | 0.79 | PDE4B (0.42) | EGFRALDH1A1 | |
| SCHEMBL27716314 | 0.76 | MAPT (0.42) | SMN1; SMN2MAPTALOX15HSD17B10SCN9A | |
| SCHEMBL4601711 | 0.76 | TSHR (0.45) | SMN1; SMN2ALDH1A1TSHRHPGDRAB9A | |
| SCHEMBL4601601 | 0.75 | EGFR (0.47) | SMN1; SMN2MAPTEGFRTHRBALDH1A1 | |
| SCHEMBL4600130 | 0.74 | EGFR (0.47) | SMN1; SMN2EGFRTHRBALDH1A1TSHR | |
| SCHEMBL4601430 | 0.74 | SCN9A (0.38) | SMN1; SMN2MAPTSCN9APOLBALDH1A1 | |
| SCHEMBL4602183 | 0.74 | EGFR (0.47) | MAPTEGFRTHRBL3MBTL1NPC1 | |
| SCHEMBL27716267 | 0.72 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTALOX15NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |