Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602165 | 0.87 | RXFP1 (0.48) | RXFP1KDM4EHTTKMT2AEGFR | |
| SCHEMBL4601218 | 0.77 | MRGPRX4 (0.46) | RXFP1KDM4EHTTKMT2AEGFR | |
| SCHEMBL27737213 | 0.74 | RXFP1 (0.45) | RXFP1KDM4EHTTKMT2AHPGD | |
| SCHEMBL4601601 | 0.74 | EGFR (0.47) | RXFP1KDM4EHTTKMT2AEGFR | |
| SCHEMBL4601338 | 0.74 | EGFR (0.42) | RXFP1KDM4EHTTKMT2AEGFR | |
| SCHEMBL4600130 | 0.73 | EGFR (0.47) | RXFP1KDM4EHTTKMT2AEGFR | |
| SCHEMBL4601416 | 0.73 | RXFP1 (0.46) | RXFP1KDM4EHTTEGFRHPGD | |
| SCHEMBL4600789 | 0.73 | HPGD (0.48) | HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL4602169 | 0.72 | EGFR (0.41) | RXFP1KDM4EHTTKMT2AEGFR | |
| SCHEMBL4602183 | 0.71 | EGFR (0.47) | KMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |