Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 2/20 | 0.39 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600204 | 0.83 | IRAK4 (0.44) | RXFP1KDM4EHPGDEGFRTP53 | |
| SCHEMBL4601601 | 0.74 | EGFR (0.47) | RXFP1KDM4EHPGDEGFRLMNA | |
| SCHEMBL4601685 | 0.73 | RXFP1 (0.48) | RXFP1KDM4EHPGDEGFRITK | |
| SCHEMBL4600130 | 0.73 | EGFR (0.47) | RXFP1KDM4EHPGDEGFRLMNA | |
| SCHEMBL4602165 | 0.72 | RXFP1 (0.48) | RXFP1KDM4EHPGDEGFRITK | |
| SCHEMBL4602183 | 0.70 | EGFR (0.47) | EGFRNPC1 | |
| SCHEMBL4600843 | 0.69 | RAB9A (0.50) | KDM4EHPGDEGFRLMNANPC1 | |
| SCHEMBL4601033 | 0.69 | EGFR (0.44) | KDM4EEGFRMRGPRX1 | |
| SCHEMBL4601338 | 0.69 | EGFR (0.42) | RXFP1KDM4EEGFRITKHTT | |
| SCHEMBL28422486 | 0.68 | KMT2A (0.43) | KDM4ETP53LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |