Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 2/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602800 | 0.81 | CHRNB2 (0.38) | GGPS1CTNNB1CHRNB2CHRNA4 | |
| SCHEMBL13779691 | 0.74 | CYP11B1 (0.40) | GGPS1CTNNB1CHRNB2CHRNA4 | |
| SCHEMBL4604870 | 0.74 | AR (0.41) | — | |
| SCHEMBL13779692 | 0.70 | CHRNB2 (0.45) | CTNNB1CHRNB2CHRNA4 | |
| SCHEMBL4205042 | 0.70 | GGPS1 (0.34) | GGPS1CTNNB1CHRNB2CHRNA4 | |
| SCHEMBL4198758 | 0.70 | CHRNB2 (0.34) | GGPS1CTNNB1CHRNB2CHRNA4 | |
| SCHEMBL30472090 | 0.70 | GGPS1 (0.45) | GGPS1CHRNB2CHRNA4 | |
| SCHEMBL25627325 | 0.70 | GGPS1 (0.45) | GGPS1CHRNB2CHRNA4 | |
| SCHEMBL6461539 | 0.67 | CTNNB1 (0.38) | CTNNB1 | |
| SCHEMBL8895538 | 0.66 | CTNNB1 (0.35) | CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915338-A2 | ANDROGEN MODULATORS | Warner-Lambert Company LLC (US) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007017754-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2007-02-15 | — | — | WO | disclosed |