Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 10/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | CHRNA6 | Q15825 | 2/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601736 | 0.81 | GGPS1 (0.40) | CHRNB2CHRNA4GGPS1CTNNB1 | |
| SCHEMBL13779692 | 0.73 | CHRNB2 (0.45) | CHRNB2CHRNA4ALDH1A1LMNACYP3A4 | |
| SCHEMBL30472090 | 0.72 | GGPS1 (0.45) | CHRNB2CHRNA4GGPS1 | |
| SCHEMBL25627325 | 0.72 | GGPS1 (0.45) | CHRNB2CHRNA4GGPS1 | |
| SCHEMBL23266068 | 0.72 | MEN1 (0.67) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL4602336 | 0.71 | AR (0.44) | — | |
| SCHEMBL13779691 | 0.71 | CYP11B1 (0.40) | CHRNB2CHRNA4GGPS1CYP3A4CTNNB1 | |
| SCHEMBL3335173 | 0.69 | LMNA (0.48) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL13354073 | 0.69 | CHRNB2 (0.79) | CHRNB2CHRNA4DAPK3ROCK2PRKCG | |
| SCHEMBL25626383 | 0.68 | CHRNB2 (0.49) | CHRNB2CHRNA4GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915338-A2 | ANDROGEN MODULATORS | Warner-Lambert Company LLC (US) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007017754-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2007-02-15 | — | — | WO | disclosed |