Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5000901 | 0.97 | TSHR (0.40) | TSHRTHRBDNM1TRPV1PTPN7 | |
| SCHEMBL26089043 | 0.92 | — | — | |
| SCHEMBL10543060 | 0.92 | — | — | |
| SCHEMBL11086709 | 0.87 | TSHR (0.44) | TSHRTHRBDNM1TRPV1HMGCR | |
| SCHEMBL887761 | 0.87 | TSHR (0.44) | TSHRTHRBDNM1TRPV1HMGCR | |
| SCHEMBL23647759 | 0.87 | TSHR (0.44) | TSHRTHRBDNM1TRPV1HMGCR | |
| SCHEMBL7527108 | 0.87 | TSHR (0.44) | TSHRTHRBDNM1TRPV1HMGCR | |
| SCHEMBL9052855 | 0.87 | TSHR (0.44) | TSHRTHRBDNM1TRPV1HMGCR | |
| SCHEMBL18037106 | 0.87 | TSHR (0.44) | TSHRTHRBDNM1TRPV1HMGCR | |
| SCHEMBL7527151 | 0.87 | TSHR (0.44) | TSHRTHRBDNM1TRPV1HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910398-A1 | 17-ALPHA-SUBSTITUTED DERIVATIVES OF ESTRADIOL WITH WOUND-HEALING ACTIVITY | Euticals S.P.A. (IT) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007014711-A1 | 17-ALPHA-SUBSTITUTED DERIVATIVES OF ESTRADIOL WITH WOUND-HEALING ACTIVITY | EUTICALS S.P.A. (IT) | 2007-02-08 | — | — | WO | disclosed |