Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006747 | 0.92 | PPARA (0.48) | PPARAALOX5PTGS2PPARGLIPG | |
| SCHEMBL29005750 | 0.84 | PPARA (0.50) | PPARAALOX5PTGS2PPARGLIPG | |
| SCHEMBL8372832 | 0.84 | THRA (0.58) | PPARAALOX5PTGS2PPARGLIPG | |
| SCHEMBL317708 | 0.84 | THRA (0.58) | PPARAALOX5PTGS2PPARGLIPG | |
| SCHEMBL8433693 | 0.84 | THRA (0.58) | PPARAALOX5PTGS2PPARGLIPG | |
| SCHEMBL28376630 | 0.84 | THRA (0.58) | PPARAALOX5PTGS2PPARGLIPG | |
| SCHEMBL29778064 | 0.84 | THRA (0.58) | PPARAALOX5PTGS2PPARGLIPG | |
| SCHEMBL10941338 | 0.83 | THRA (0.49) | PPARAALOX5PTGS2PPARGLIPG | |
| SCHEMBL10348761 | 0.82 | THRA (0.56) | PPARAALOX5PTGS2PPARGLIPG | |
| SCHEMBL29197409 | 0.81 | PTGS2 (0.60) | PPARAALOX5PTGS2PPARGLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0905184-B1 | Aromatic polycarbonate resin composition | GEN ELECTRIC (US) | 2008-04-23 | — | — | EP | disclosed |
| US-5973101-A | COMPRISING A STABILIZER DEACTIVATING THE METAL IMPURITY, PREVENTING THE INTERACTION OF HYDROXYL END GROUPS OF POLYCARBONATES WITH METALS | GENERAL ELECTRIC COMPANY (US) | 1999-10-26 | — | — | US | disclosed |
| EP-0905184-A2 | Aromatic polycarbonate resin composition | GENERAL ELECTRIC COMPANY (US) | 1999-03-31 | — | — | EP | disclosed |