Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 16/20 | 0.45 |
| ▸ | MC5R | P33032 | 5/20 | 0.43 |
| ▸ | MC1R | Q01726 | 4/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | PDE9A | O76083 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29327333 | 1.00 | DRD2 (0.46) | DRD2DRD3MC4RMC5RMC1R | |
| SCHEMBL1920455 | 1.00 | DRD2 (0.46) | DRD2DRD3MC4RMC5RMC1R | |
| SCHEMBL1921872 | 1.00 | DRD2 (0.46) | DRD2DRD3MC4RMC5RMC1R | |
| SCHEMBL13493013 | 0.92 | DRD2 (0.39) | DRD2DRD3MC4RMC5RMC1R | |
| SCHEMBL21036550 | 0.92 | DRD2 (0.43) | DRD2DRD3MC4RMC5RMC1R | |
| SCHEMBL5924057 | 0.91 | DPP4 (0.42) | DRD2DRD3MC4R | |
| SCHEMBL1947750 | 0.90 | DRD2 (0.49) | DRD2DRD3MC4R | |
| SCHEMBL7657908 | 0.88 | CCR5 (0.45) | DRD2DRD3MC4R | |
| SCHEMBL7657911 | 0.88 | CCR5 (0.45) | DRD2DRD3MC4R | |
| SCHEMBL1970494 | 0.87 | RORC (0.46) | DRD2DRD3MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912968-A1 | PIPERIDINOYL-PYRROLIDINE AND PIPERIDINOYL-PIPERIDINE COMPOUNDS | Pfizer Limited (GB) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007015162-A1 | PIPERIDINOYL-PYRROLIDINE AND PIPERIDINOYL-PIPERIDINE COMPOUNDS | PFIZER LIMITED (GB) | 2007-02-08 | — | — | WO | disclosed |