SCHEMBL4602011

SCHEMBL4602011

CCCCCCCCN(C=S)CCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 7/20 0.48
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
TSHR P16473 4/20 0.42
THRB P10828 1/20 0.42
MGLL Q99685 1/20 0.39
ADH1C P00326 1/20 0.38
ADH1A P07327 1/20 0.38
ADH4 P08319 1/20 0.38
HTT P42858 1/20 0.36
GBA1 P04062 1/20 0.35
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL270407 1.00 DNM1 (0.48) DNM1CA12CA1CA2CA9
SCHEMBL271649 1.00 DNM1 (0.48) DNM1CA12CA1CA2CA9
SCHEMBL271233 0.97 DNM1 (0.46) DNM1CA12CA1CA2CA9
SCHEMBL270639 0.97 DNM1 (0.43) DNM1CA12CA1CA2CA9
SCHEMBL269626 0.95 DNM1 (0.44) DNM1CA12CA1CA2CA9
SCHEMBL269573 0.95 DNM1 (0.42) DNM1CA12CA1CA2CA9
SCHEMBL270747 0.92 DNM1 (0.40) DNM1CA12CA1CA2CA9
SCHEMBL271652 0.90 DNM1 (0.44) DNM1CA12CA1CA2CA9
SCHEMBL269464 0.89 ALDH1A1 (0.37) DNM1CA12CA1CA2CA9
SCHEMBL269999 0.87 DNM1 (0.40) DNM1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1694748-B1 METHOD OF MODIFYING A FLUOROPOLYMERIC SUBSTRATE AND COMPOSITE ARTICLES THEREBY 3M INNOVATIVE PROPERTIES CO (US) 2008-04-23 EP disclosed
US-7273531-B2 Method of modifying a fluoropolymeric substrate and composite articles thereby 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-09-25 US disclosed
EP-1694748-A1 METHOD OF MODIFYING A FLUOROPOLYMERIC SUBSTRATE AND COMPOSITE ARTICLES THEREBY 3M Innovative Properties Company (US) 2006-08-30 EP disclosed
WO-2005047373-A1 METHOD OF MODIFYING A FLUOROPOLYMERIC SUBSTRATE AND COMPOSITE ARTICLES THEREBY 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-05-26 WO disclosed
US-20050092429-A1 Method of modifying a fluoropolymeric substrate and composite articles thereby 3M INNOVATIVE PROPERTIES COMPANY 2005-05-05 US disclosed