Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4632919 | 0.84 | — | — | |
| SCHEMBL24818591 | 0.80 | ANPEP (0.33) | ANPEP | |
| SCHEMBL24819071 | 0.77 | CYP2D6 (0.33) | ANPEP | |
| SCHEMBL24818476 | 0.77 | ANPEP (0.31) | ANPEP | |
| SCHEMBL21594121 | 0.76 | — | — | |
| SCHEMBL23374697 | 0.75 | CYP2D6 (0.35) | ANPEP | |
| SCHEMBL27410010 | 0.75 | ANPEP (0.31) | ANPEP | |
| SCHEMBL4600596 | 0.72 | CHRNB2 (0.31) | — | |
| SCHEMBL15910941 | 0.70 | — | — | |
| SCHEMBL22433613 | 0.69 | HSD11B1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124085-A2 | METHODS OF USING COMBINATIONS OF MEK AND JAK-2 INHIBITORS | EXELIXIS, INC. (US) | 2008-10-16 | — | — | WO | disclosed |