Trolamine

Trolamine

SCHEMBL4602325

CC(O)CNCC(C)O.OCCN(CCO)CCO

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.35
MAPT P10636 1/20 0.32
ALDH1A1 P00352 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
LMNA P02545 1/20 0.31
ADRB2 P07550 1/20 0.30
SLC29A1 Q99808 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL28217910 0.84 CYP2C9 (0.36) TDP1ALDH1A1LMNAADRB2
Trolamine SCHEMBL8385039 0.79 TDP1 (0.59) TDP1MAPTALDH1A1CYP1A2LMNA
Trolamine SCHEMBL27756311 0.79 MAPT (0.42) TDP1MAPTALDH1A1CYP1A2LMNA
Trolamine SCHEMBL6682064 0.79 MAPT (0.42) TDP1MAPTALDH1A1CYP1A2LMNA
Trolamine SCHEMBL8515537 0.79 MAPT (0.42) TDP1MAPTALDH1A1CYP1A2LMNA
Trolamine SCHEMBL6455111 0.79 MAPT (0.42) TDP1MAPTALDH1A1CYP1A2LMNA
Diisopropanolamine SCHEMBL10618901 0.79
Diisopropanolamine SCHEMBL22774 0.79
SCHEMBL14980624 0.79 ADRB2 (0.33) ALDH1A1ADRB2
Trolamine SCHEMBL10425247 0.77 TSHR (0.56) TDP1MAPTALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957581-B Modified melamine resin and preparation method thereof, dust collecting plate and air purifier 珠海格力电器股份有限公司 2023-07-18 CN disclosed
CN-114957581-A Modified melamine resin, preparation method thereof, dust collecting plate and air purifier 珠海格力电器股份有限公司 2022-08-30 CN disclosed
US-10822500-B2 Preparations as hydrophobing agents RUDOLF GMBH (DE) 2020-11-03 US disclosed
US-20190309174-A1 PREPARATION AS WATER REPELLING AGENTS RUDOLF GMBH (DE) 2019-10-10 US disclosed
EP-1457480-B1 Tertiary alkanolamines containing surface active alkyl groups AIR PROD & CHEM (US) 2008-11-19 EP disclosed
EP-1435363-B1 Improving the physical properties of polyurethane foams using tertiary amino alkyl amide catalysts AIR PROD & CHEM (US) 2008-04-23 EP disclosed
EP-1457507-B1 Tertiary alkanolamine polyurethane catalysts derived from long chain alkyl and fatty carboxylic acids AIR PROD & CHEM (US) 2008-04-23 EP disclosed
EP-1435365-B1 Tertiary amino alkyl amide catalysts for improving the physical properties of polyurethane foams AIR PROD & CHEM (US) 2007-06-13 EP disclosed
US-7192990-B2 Tertiary amino alkyl amide polyurethane catalysts derived from long chain alkyl and fatty carboxylic acids AIR PRODUCTS AND CHEMICALS, INC. (US) 2007-03-20 US disclosed
US-7189765-B2 Improving the physical properties of polyurethane foams using tertiary amino alkyl amide catalysts AIR PRODUCTS AND CHEMICALS, INC. (US) 2007-03-13 US disclosed
US-20040132851-A1 Tertiary amino alkyl amide polyurethane catalysts derived from long chain alkyl and fatty carboxylic acids AIR PRODUCTS AND CHEMICALS, INC. 2004-07-08 US disclosed
US-20040132850-A1 Tertiary amino alkyl amide catalysts for improving the physical properties of polyurethane foams AIR PRODUCTS AND CHEMICALS, INC. 2004-07-08 US disclosed
US-20040132847-A1 TERTIARY AMINO ALKYL AMIDE POLYURETHANE CATALYSTS DERIVED FROM LONG CHAIN ALKYL AND FATTY CARBOXYLIC ACIDS EVONIK DEGUSSA GMBH (DE) 2004-07-08 US disclosed
EP-1435364-A2 Tertiary amino alkyl amide polyurethane catalysts derived from long chain alkyl or fatty carboxylic acids AIR PRODUCTS AND CHEMICALS, INC. (US) 2004-07-07 EP disclosed
EP-1435363-A2 Improving the physical properties of polyurethane foams using tertiary amino alkyl amide catalysts AIR PRODUCTS AND CHEMICALS, INC. (US) 2004-07-07 EP disclosed
EP-1435365-A2 Tertiary amino alkyl amide catalysts for improving the physical properties of polyurethane foams AIR PRODUCTS AND CHEMICALS, INC. (US) 2004-07-07 EP disclosed
US-6759447-B1 MINIMIZING SHRINKAGE; IMPROVING DIMENSIONAL STABILITY AIR PRODUCTS AND CHEMICALS, INC. 2004-07-06 US disclosed
US-6747069-B1 PREPARING A POLYURETHANE FOAM WHICH COMPRISES REACTING AN ORGANIC POLYISOCYANATE AND A POLYOL IN THE PRESENCE OF WATER AS A BLOWING AGENT, A CELL STABILIZER, AND A TERTIARY AMINE AMIDE CATALYST COMPOSITION AIR PRODUCTS AND CHEMICALS, INC. 2004-06-08 US disclosed
US-6737446-B1 POROSITY, OPENNESS; DIMENSIONAL STABILITY AIR PRODUCTS AND CHEMICALS, INC. 2004-05-18 US disclosed
WO-1989011327-A1 LIQUID ABSORBING ACID GASES SOCIETE NATIONALE ELF AQUITAINE (PRODUCTION) (FR) 1989-11-30 WO disclosed