Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | PGR | P06401 | 2/20 | 0.72 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | PDE4A | P27815 | 1/20 | 0.72 |
| ▸ | HRH1 | P35367 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.72 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.63 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9002553 | 0.91 | HPGD (0.61) | HPGDLMNAALDH1A1MAPK1CYP1A2 | |
| SCHEMBL12800314 | 0.91 | LMNA (0.72) | HPGDLMNAALDH1A1MAPK1CYP1A2 | |
| SCHEMBL20496424 | 0.90 | ALDH1A1 (0.58) | HPGDLMNAALDH1A1MAPK1CYP1A2 | |
| SCHEMBL29415012 | 0.90 | ALDH1A1 (0.58) | HPGDLMNAALDH1A1MAPK1CYP1A2 | |
| SCHEMBL4150542 | 0.89 | LMNA (0.70) | HPGDLMNAALDH1A1MAPK1CYP1A2 | |
| SCHEMBL9002666 | 0.87 | NPC1 (0.67) | HPGDLMNAALDH1A1MAPK1CYP1A2 | |
| SCHEMBL30374998 | 0.86 | KMT2A (0.57) | HPGDLMNAALDH1A1MAPK1CYP1A2 | |
| SCHEMBL20496445 | 0.86 | HPGD (0.66) | HPGDLMNAALDH1A1MAPK1CYP1A2 | |
| SCHEMBL5710117 | 0.86 | KMT2A (0.57) | HPGDLMNAALDH1A1MAPK1CYP1A2 | |
| SCHEMBL29415033 | 0.86 | HPGD (0.66) | HPGDLMNAALDH1A1MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940345-A1 | HAIR-TREATMENT COMPOSITIONS WITH IMPROVED CARE PERFORMANCE AND METHOD FOR APPLYING THE COMPOSITION | Henkel AG & Co. KGaA (DE) | 2008-07-09 | — | — | EP | claimed |
| WO-2007048486-A1 | HAIR-TREATMENT COMPOSITIONS WITH IMPROVED CARE PERFORMANCE AND METHOD FOR APPLYING THE COMPOSITION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-05-03 | — | — | WO | claimed |
| US-7988953-B2 | cosmetic; dendritic polyether; sunscreens | DSM IP ASSETS B.V. (NL) | 2011-08-02 | — | — | US | disclosed |
| US-7988953-B2 | cosmetic; dendritic polyether; sunscreens | DSM IP ASSETS B.V. (NL) | 2011-08-02 | — | — | US | disclosed |
| EP-2116585-A1 | ULTRAVIOLET ABSORBER COMPOSITION | Fujifilm Corporation (JP) | 2009-11-11 | — | — | EP | disclosed |
| EP-1940345-A1 | HAIR-TREATMENT COMPOSITIONS WITH IMPROVED CARE PERFORMANCE AND METHOD FOR APPLYING THE COMPOSITION | Henkel AG & Co. KGaA (DE) | 2008-07-09 | — | — | EP | disclosed |
| US-20080081025-A1 | Uv Absorbing Chromophores Covalently Bonded to Hyperbranched Polymers | DSM IP ASSETS B.V. (NL) | 2008-04-03 | — | — | US | disclosed |
| US-20080081025-A1 | Uv Absorbing Chromophores Covalently Bonded to Hyperbranched Polymers | DSM IP ASSETS B.V. (NL) | 2008-04-03 | — | — | US | disclosed |
| WO-2007048486-A1 | HAIR-TREATMENT COMPOSITIONS WITH IMPROVED CARE PERFORMANCE AND METHOD FOR APPLYING THE COMPOSITION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-05-03 | — | — | WO | disclosed |
| EP-1265588-A2 | ANTIPLAQUE ORAL COMPOSITION | Colgate-Palmolive Company (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001064169-A2 | ANTIPLAQUE ORAL COMPOSITION | COLGATE-PALMOLIVE COMPANY (US) | 2001-09-07 | — | — | WO | disclosed |
| US-6235268-B1 | Antiplaque oral composition and method | COLGATE-PALMOLIVE COMPANY | 2001-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081025-A1 | Uv Absorbing Chromophores Covalently Bonded to Hyperbranched Polymers | PCNA, MMS19, ERCC4 | HPGD 393/4885LMNA 1092/4885ALDH1A1 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.