SCHEMBL4602590

SCHEMBL4602590

CO[Si](C)(CCCOC(=O)C1(C)CC2C=CC1C2)OC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.33
CETP P11597 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL294664 0.90 P2RX7 (0.34) P2RX7CETP
SCHEMBL14559748 0.86 P2RX7 (0.34) P2RX7CETP
SCHEMBL6747504 0.85 P2RX7 (0.34) P2RX7
SCHEMBL202743 0.82 P2RX7 (0.33) P2RX7
SCHEMBL5186809 0.82 P2RX7 (0.34) P2RX7CETP
SCHEMBL200578 0.82 CYP2C19 (0.36) P2RX7CETP
SCHEMBL32689139 0.81 EPHX2 (0.38) P2RX7
SCHEMBL29326086 0.80 P2RX7 (0.35) P2RX7CETP
SCHEMBL4253408 0.79 P2RX7 (0.36) P2RX7CETP
SCHEMBL21593923 0.79 P2RX7 (0.36) P2RX7CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1364975-B1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR CORP (JP) 2008-04-30 EP disclosed
US-20070225461-A1 Olefin polymers for imaging members LEXMARK INTERNATIONAL INC. 2007-09-27 US disclosed
US-20070112158-A1 Novel (co)polymer, process for producing the same, and process for producing carboxylated (co)polymer JSR CORPORATION (JP) 2007-05-17 US disclosed
EP-1686139-A1 NOVEL (CO)POLYMER, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING CARBOXYLATED (CO)POLYMER JSR Corporation (JP) 2006-08-02 EP disclosed
US-6911507-B2 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2005-06-28 US disclosed
US-20040063873-A1 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2004-04-01 US disclosed
EP-1364975-A1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR Corporation (JP) 2003-11-26 EP disclosed