SCHEMBL200578

SCHEMBL200578

CCCCOC(=O)C1(C)CC2C=CC1C2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.36
CYP2D6 P10635 2/20 0.36
ALDH1A1 P00352 1/20 0.36
P2RX7 Q99572 1/20 0.34
ATM Q13315 1/20 0.34
EPHX2 P34913 4/20 0.33
TSHR P16473 4/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ESR1 P03372 3/20 0.33
HPGD P15428 1/20 0.33
LMNA P02545 3/20 0.32
CYP1A2 P05177 2/20 0.32
MAPK1 P28482 1/20 0.32
NR1H2 P55055 1/20 0.32
RNASEL Q05823 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CETP P11597 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32689139 0.96 EPHX2 (0.38) CYP2C19CYP2D6ALDH1A1P2RX7EPHX2
SCHEMBL201163 0.91 CYP2D6 (0.38) CYP2C19CYP2D6ALDH1A1P2RX7EPHX2
SCHEMBL5186809 0.89 P2RX7 (0.34) CYP2C19CYP2D6P2RX7CETP
SCHEMBL14628487 0.85 P2RX7 (0.36) CYP2C19CYP2D6ALDH1A1P2RX7CETP
SCHEMBL21593923 0.85 P2RX7 (0.36) CYP2C19CYP2D6ALDH1A1P2RX7CETP
SCHEMBL4253408 0.85 P2RX7 (0.36) CYP2C19CYP2D6ALDH1A1P2RX7CETP
SCHEMBL200228 0.85 CYP2C19 (0.40) CYP2C19CYP2D6P2RX7TSHRLMNA
SCHEMBL7204575 0.84 CYP2C19 (0.37) CYP2C19CYP2D6ALDH1A1ATMEPHX2
SCHEMBL294664 0.84 P2RX7 (0.34) CYP2C19CYP2D6P2RX7CETP
SCHEMBL6747504 0.84 P2RX7 (0.34) CYP2C19CYP2D6P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0263425-A1 A process and composition for metathesis polymerization of cycloolefins HERCULES INCORPORATED (US) 1988-04-13 EP claimed
CN-119371641-A Cyclic olefin ring-opening polymer and hydride thereof 杭州睿丰融创科技有限公司 2025-01-28 CN disclosed
CN-110366704-B Radiation-sensitive resin composition and electronic component 日本瑞翁株式会社(JP) 2023-01-13 CN disclosed
CN-108885398-B Radiation-sensitive resin composition and electronic component 日本瑞翁株式会社 2022-11-29 CN disclosed
CN-114402258-A Radiation-sensitive resin composition 日本瑞翁株式会社 2022-04-26 CN disclosed
US-11169440-B2 Radiation-sensitive resin composition and electronic component ZEON CORPORATION (JP) 2021-11-09 US disclosed
EP-3345970-B1 RESIN COMPOSITION ZEON CORP (JP) 2021-07-28 EP disclosed
EP-3434731-B1 RESIN COMPOSITION, RESIN FILM, AND ELECTRONIC DEVICE ZEON CORP (JP) 2021-06-09 EP disclosed
CN-108779317-B Resin composition, resin film, and electronic component 日本瑞翁株式会社 2021-04-16 CN disclosed
CN-107922742-B Resin composition 日本瑞翁株式会社 2021-01-15 CN disclosed
EP-1048983-A1 Radiation sensitive resin composition JSR Corporation (JP) 2000-11-02 EP disclosed
EP-1034196-A1 CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS THE B.F. GOODRICH COMPANY (US) 2000-09-13 EP disclosed
WO-2000020472-A1 CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS THE B.F. GOODRICH COMPANY (US) 2000-04-13 WO disclosed
EP-0930541-A1 Radiation sensitive resin composition JSR Corporation (JP) 1999-07-21 EP disclosed
EP-0698620-B1 Method for preparing modified resins and their applications MITSUI CHEMICALS INC (JP) 1998-12-09 EP disclosed
EP-0849634-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-06-24 EP disclosed
EP-0789278-A2 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-08-13 EP disclosed
EP-0698620-A1 Method for preparing modified resins and their applications MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-02-28 EP disclosed
US-5064919-A Catalytic RIM of a dicyclopentadiene and a norbornene-type monomer containing an N-substituted cyclic imide group using a molybdenum or tungsten salt and alkylaluminum activator HERCULES INCORPORATED (US) 1991-11-12 US disclosed
EP-0263425-A1 A process and composition for metathesis polymerization of cycloolefins HERCULES INCORPORATED (US) 1988-04-13 EP disclosed