SCHEMBL6747504

SCHEMBL6747504

CC1(C(=O)OCCC[Si](Cl)(Cl)Cl)CC2C=CC1C2

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.34
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14559748 0.91 P2RX7 (0.34) P2RX7CYP2D6CYP2C19
SCHEMBL294664 0.87 P2RX7 (0.34) P2RX7CYP2D6CYP2C19
SCHEMBL4602590 0.85 P2RX7 (0.33) P2RX7
SCHEMBL202743 0.84 P2RX7 (0.33) P2RX7CYP2D6CYP2C19
SCHEMBL200578 0.84 CYP2C19 (0.36) P2RX7CYP2D6CYP2C19
SCHEMBL5186809 0.84 P2RX7 (0.34) P2RX7CYP2D6CYP2C19
SCHEMBL32689139 0.83 EPHX2 (0.38) P2RX7CYP2D6CYP2C19
SCHEMBL14628487 0.81 P2RX7 (0.36) P2RX7CYP2D6CYP2C19
SCHEMBL201163 0.81 CYP2D6 (0.38) P2RX7CYP2D6CYP2C19
SCHEMBL21593923 0.81 P2RX7 (0.36) P2RX7CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6790914-B2 TRANSPARENT (CROSSLINKED) RESIN FILM CAN BE USED AS A POLARIZING FILM, SURFACE PROTECTIVE FILM, RETARDATION FILM, TRANSPARENT CONDUCTIVE FILM, LIGHT DIFFUSION FILM, FILM FOR AN EL DISPLAY DEVICE, TRANSPARENT CONDUCTIVE COMPOSITE MATERIAL, JSR CORPORATION (JP) 2004-09-14 US disclosed
US-20040106740-A1 Resin film and applications thereof JSR CORPORATION (JP) 2004-06-03 US disclosed
EP-1195397-B1 Composition of cyclic olefin addition copolymer and cross-linked material JSR CORP (JP) 2004-04-14 EP disclosed
US-20020042461-A1 Composition of cyclic olefin addition copolymer and cross-linked material JSR CORPORATION (JP) 2002-04-11 US disclosed
EP-1195397-A1 Composition of cyclic olefin addition copolymer and cross-linked material JSR Corporation (JP) 2002-04-10 EP disclosed