Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 6/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL28583220 | 0.80 | LMNA (0.56) | LMNAALDH1A1GABRR1GABBR2GABBR1 | |
| Glycerin SCHEMBL5488218 | 0.80 | LMNA (0.56) | LMNAALDH1A1GABRR1GABBR2GABBR1 | |
| Glycerin SCHEMBL579432 | 0.80 | LMNA (0.64) | LMNAALDH1A1ANPEPGABRR1GABBR2 | |
| Glycerin SCHEMBL888512 | 0.80 | LMNA (0.64) | LMNAALDH1A1ANPEPGABRR1GABBR2 | |
| Glycerin SCHEMBL188342 | 0.80 | LMNA (0.64) | LMNAALDH1A1ANPEPGABRR1GABBR2 | |
| Glycerin SCHEMBL30710214 | 0.80 | LMNA (0.64) | LMNAALDH1A1ANPEPGABRR1GABBR2 | |
| Glycerin SCHEMBL21101 | 0.80 | LMNA (0.64) | LMNAALDH1A1ANPEPGABRR1GABBR2 | |
| Glycerin SCHEMBL31106042 | 0.80 | LMNA (0.64) | LMNAALDH1A1ANPEPGABRR1GABBR2 | |
| Glycerin SCHEMBL10562963 | 0.77 | LMNA (0.60) | LMNAALDH1A1GABRR1GABBR2GABBR1 | |
| Glycerin SCHEMBL1792712 | 0.77 | LMNA (0.60) | LMNAALDH1A1GABRR1GABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575282-B2 | Compound modified by a phosphoramidate and/or phosphonamide group and use thereof | FREIE UNIVERSITAET BERLIN (DE) | 2013-11-05 | — | — | US | disclosed |
| US-20120065344-A1 | COMPOUND MODIFIED BY A PHOSPHORAMIDATE AND/OR PHOSPHONAMIDE GROUP AND USE THEREOF | FREIE UNIVERSITAET BERLIN (DE) | 2012-03-15 | — | — | US | disclosed |