Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601982 | 0.76 | MPI (0.34) | MPITDP1 | |
| SCHEMBL10881499 | 0.75 | MAPT (0.39) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL10882872 | 0.74 | SMN1; SMN2 (0.39) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL4602885 | 0.73 | MPI (0.41) | MPITDP1 | |
| SCHEMBL10882989 | 0.72 | MAPT (0.37) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL4603246 | 0.69 | MEN1 (0.42) | MEN1KMT2AMPITDP1ALDH1A1 | |
| SCHEMBL2459084 | 0.67 | KDM4E (0.52) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2459082 | 0.67 | KDM4E (0.52) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3914119 | 0.64 | LMNA (0.56) | LMNAMAPTPOLBNPC1RAB9A | |
| SCHEMBL4603585 | 0.64 | MPI (0.41) | MPITDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194633-B1 | AGENT FOR COLORING FIBERS AND METHOD FOR TEMPORARILY COLORING FIBERS | WELLA AG (DE) | 2008-04-30 | — | — | EP | claimed |
| EP-1341503-B1 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2008-02-13 | — | — | EP | claimed |
| EP-1227786-B1 | AGENT FOR DYEING FIBRES COMPRISING AN INDOLINE/INDOLIUM DERIVATIVE | WELLA AG (DE) | 2005-08-24 | — | — | EP | claimed |
| US-6835212-B2 | Compound with a nucleophilic reaction center, aryl alcohol or benzyl alcohol derivatives and an oxidizing enzyme | WELLA AKTIENGESELLSCHAFT (DE) | 2004-12-28 | — | — | US | claimed |
| US-6669739-B2 | Agent for coloring fibers and method for temporarily coloring fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2003-12-30 | — | — | US | claimed |
| US-6652601-B2 | For dyeing and subsequently decolorizing fibers such as keratin fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2003-11-25 | — | — | US | claimed |
| EP-1341503-A2 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 2003-09-10 | — | — | EP | claimed |
| US-20030079301-A1 | Agent for dyeing fibers comprising an indoline/indolium derivative | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-05-01 | — | — | US | claimed |
| US-20030041391-A1 | Agent and method for dyeing keratin fibres | Wella GmbH (DE) | 2003-03-06 | — | — | US | claimed |
| US-20020172651-A1 | Agent for coloring fibers and method for temporarily coloring fibers | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2002-11-21 | — | — | US | claimed |
| EP-1227786-A1 | AGENT FOR DYEING FIBRES COMPRISING AN INDOLINE/INDOLIUM DERIVATIVE | Wella Aktiengesellschaft (DE) | 2002-08-07 | — | — | EP | claimed |
| WO-2002047633-A2 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-06-20 | — | — | WO | claimed |
| WO-2001062219-A1 | AGENT FOR DYEING FIBRES COMPRISING AN INDOLINE/INDOLIUM DERIVATIVE | WELLA AKTIENGESELLSCHAFT (DE) | 2001-08-30 | — | — | WO | claimed |
| EP-1194633-B1 | AGENT FOR COLORING FIBERS AND METHOD FOR TEMPORARILY COLORING FIBERS | WELLA AG (DE) | 2008-04-30 | — | — | EP | disclosed |
| EP-1699427-B1 | AGENT AND METHOD FOR OXIDATIVELY DYING KERATIN FIBERS | WELLA AG (DE) | 2008-02-27 | — | — | EP | disclosed |
| EP-1341503-B1 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2008-02-13 | — | — | EP | disclosed |
| WO-2002047633-A2 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-06-20 | — | — | WO | disclosed |
| EP-1194633-A1 | AGENT FOR COLORING FIBERS AND METHOD FOR TEMPORARILY COLORING FIBERS | Wella Aktiengesellschaft (DE) | 2002-04-10 | — | — | EP | disclosed |
| WO-2001086057-A1 | AGENT FOR COLORING FIBERS AND METHOD FOR TEMPORARILY COLORING FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2001-11-15 | — | — | WO | disclosed |
| WO-2001062219-A1 | AGENT FOR DYEING FIBRES COMPRISING AN INDOLINE/INDOLIUM DERIVATIVE | WELLA AKTIENGESELLSCHAFT (DE) | 2001-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030079301-A1 | Agent for dyeing fibers comprising an indoline/indolium derivative | IDO1, IDO2, KIT | LMNA 429/4885MAPT 1104/4885POLB 1697/4885 |
| US-20020172651-A1 | Agent for coloring fibers and method for temporarily coloring fibers | ENO1, H1-5, H1-2 | LMNA 344/4885MAPT 1635/4885POLB 1669/4885 |
| US-20030041391-A1 | Agent and method for dyeing keratin fibres | KRT18, AKR7A2, ADH5 | LMNA 671/4885MAPT 844/4885POLB 492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.