Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28481363 | 0.99 | BACE1 (0.35) | BACE1BACE2MEN1ALDH1A1CYP2C9 | |
| SCHEMBL28491022 | 0.89 | — | — | |
| Succinimide SCHEMBL9845552 | 0.81 | BACE1 (0.41) | BACE1BACE2MEN1ALDH1A1CYP2C9 | |
| SCHEMBL159817 | 0.80 | LMNA (0.46) | BACE1BACE2MEN1ALDH1A1CYP2C9 | |
| SCHEMBL890390 | 0.80 | LMNA (0.46) | BACE1BACE2MEN1ALDH1A1CYP2C9 | |
| Hydrochloric Acid SCHEMBL25415692 | 0.78 | LMNA (0.44) | BACE1BACE2MEN1ALDH1A1CYP2C9 | |
| SCHEMBL28063070 | 0.75 | BACE1 (0.36) | BACE1BACE2MEN1ALDH1A1CYP2C9 | |
| Succinic Acid SCHEMBL23234379 | 0.75 | PTGS1 (0.42) | BACE1BACE2MEN1ALDH1A1CYP2C9 | |
| SCHEMBL9843326 | 0.73 | LMNA (0.32) | MEN1ALDH1A1KMT2ALMNA | |
| Bicarbonate SCHEMBL28576915 | 0.72 | MAP3K14 (0.39) | MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114316016-A | Method for biotinylation of Jo-1 antigen and anti-Jo-1 antibody detection kit | 江苏浩欧博生物医药股份有限公司 | 2022-04-12 | — | — | CN | claimed |
| US-20040234521-A1 | Polyclonal populations of bispecific molecules and methods of production and uses thereof | ELUSYS THERAPEUTICS, INC | 2004-11-25 | — | — | US | claimed |
| CN-115541750-A | Method for detecting heterobifunctional cross-linking agent | 上海凌凯医药科技有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115298219-A | Use of multispecific antibodies for the treatment of several diseases | 耶达研究及发展有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-115175927-A | Immunogenic conjugates aimed at inducing an immune response to interleukin-6 | 佩普蒂诺夫公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-115052663-A | ALK5 inhibitor conjugates and uses thereof | 辛瑟斯治疗股份有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-114269388-A | antibody-ALK 5 inhibitor conjugates and uses thereof | 辛瑟斯治疗股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-112601522-A | antibody-ALK 5 inhibitor conjugates and uses thereof | 辛瑟斯治疗股份有限公司 | 2021-04-02 | — | — | CN | disclosed |
| EP-1379277-A4 | POLYCLONAL POPULATIONS OF BISPECIFIC MOLECULES AND METHODS OF PRODUCTION AND USES THEREOF | ELUSYS THERAPEUTICS INC (US) | 2008-09-17 | — | — | EP | disclosed |
| EP-1487487-A2 | METHODS AND COMPOSITIONS FOR PREVENTION, DIAGNOSIS, AND TREATMENT OF CANCER USING BISPECIFIC MOLECULES | Elusys Therapeutics, Inc. (US) | 2004-12-22 | — | — | EP | disclosed |
| US-20040234521-A1 | Polyclonal populations of bispecific molecules and methods of production and uses thereof | ELUSYS THERAPEUTICS, INC | 2004-11-25 | — | — | US | disclosed |
| EP-1379277-A2 | POLYCLONAL POPULATIONS OF BISPECIFIC MOLECULES AND METHODS OF PRODUCTION AND USES THEREOF | Elusys Therapeutics, Inc. (US) | 2004-01-14 | — | — | EP | disclosed |
| WO-2003026490-A2 | METHODS AND COMPOSITIONS FOR PREVENTION, DIAGNOSIS, AND TREATMENT OF CANCER USING BISPECIFIC MOLECULES | ELUSYS THERAPEUTICS, INC. (US) | 2003-04-03 | — | — | WO | disclosed |
| US-20030059401-A1 | Composition and method for causing photodynamic damage to target cells | SOBOLEV ALEXANDER SERGEEVICH (RU) | 2003-03-27 | — | — | US | disclosed |
| US-6500800-B1 | Composition and method for causing photodynamic damage to target cells | SOBOLEV ALEXANDER SERGEEVICH (RU) | 2002-12-31 | — | — | US | disclosed |
| WO-2002075275-A2 | POLYCLONAL POPULATIONS OF BISPECIFIC MOLECULES AND METHODS OF PRODUCTION AND USES THEREOF | ELUSYS THERAPEUTICS, INC. (US) | 2002-09-26 | — | — | WO | disclosed |