Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | WRN | Q14191 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28226110 | 0.75 | GSK3A (0.44) | LMNAMEN1APEX1KMT2ATDP1 | |
| SCHEMBL14392724 | 0.74 | LMNA (0.40) | LMNAMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL22650155 | 0.74 | ALDH1A1 (0.37) | LMNAALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL1421996 | 0.74 | CHRM2 (0.39) | MEN1APEX1KMT2ATDP1L3MBTL1 | |
| SCHEMBL15563667 | 0.74 | — | — | |
| SCHEMBL23234378 | 0.73 | ALDH1A1 (0.39) | LMNAALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL4602809 | 0.73 | BACE1 (0.35) | LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL4450426 | 0.73 | PTGS1 (0.36) | LMNAALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL18033768 | 0.72 | ALDH1A1 (0.36) | LMNAMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL27792437 | 0.72 | ALDH1A1 (0.35) | LMNAALDH1A1CYP1A2HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011770-A | Complexing with labeled protein; quantitative analysis | MOLECULAR DEVICES, INC. (US) | 1991-04-30 | — | — | US | disclosed |