Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 5/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 5/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27371331 | 0.98 | CA2 (0.53) | CA2FAAHSOAT1MEN1TP53 | |
| SCHEMBL3164396 | 0.98 | CA2 (0.53) | CA2FAAHSOAT1MEN1TP53 | |
| SCHEMBL4302839 | 0.98 | CA2 (0.53) | CA2FAAHSOAT1MEN1TP53 | |
| SCHEMBL27396124 | 0.98 | CA2 (0.53) | CA2FAAHSOAT1MEN1TP53 | |
| SCHEMBL7400053 | 0.94 | FAAH (0.44) | CA2FAAHSOAT1MEN1TP53 | |
| SCHEMBL6637023 | 0.92 | CA2 (0.55) | CA2FAAHSOAT1MEN1TP53 | |
| SCHEMBL8759772 | 0.92 | CA2 (0.55) | CA2FAAHSOAT1MEN1TP53 | |
| SCHEMBL14166661 | 0.92 | FAAH (0.57) | CA2FAAHSOAT1MEN1TP53 | |
| SCHEMBL4732708 | 0.92 | FAAH (0.57) | CA2FAAHSOAT1MEN1TP53 | |
| SCHEMBL4731981 | 0.92 | FAAH (0.57) | CA2FAAHSOAT1MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |