Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.57 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 5/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | PPARD | Q03181 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732397 | 1.00 | FAAH (0.57) | FAAHSOAT1MEN1KMT2ATP53 | |
| SCHEMBL14166661 | 1.00 | FAAH (0.57) | FAAHSOAT1MEN1KMT2ATP53 | |
| SCHEMBL4731981 | 1.00 | FAAH (0.57) | FAAHSOAT1MEN1KMT2ATP53 | |
| SCHEMBL6637023 | 0.96 | CA2 (0.55) | FAAHSOAT1MEN1KMT2ATP53 | |
| SCHEMBL8759772 | 0.96 | CA2 (0.55) | FAAHSOAT1MEN1KMT2ATP53 | |
| SCHEMBL27396124 | 0.94 | CA2 (0.53) | FAAHSOAT1MEN1KMT2ATP53 | |
| SCHEMBL4302839 | 0.94 | CA2 (0.53) | FAAHSOAT1MEN1KMT2ATP53 | |
| SCHEMBL27371331 | 0.94 | CA2 (0.53) | FAAHSOAT1MEN1KMT2ATP53 | |
| SCHEMBL3164396 | 0.94 | CA2 (0.53) | FAAHSOAT1MEN1KMT2ATP53 | |
| SCHEMBL4602871 | 0.92 | CA2 (0.50) | FAAHSOAT1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008044033-A1 | AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-04-17 | — | — | WO | disclosed |