SCHEMBL4602929

SCHEMBL4602929

CCO[Si](CCCC1CC2C=CC1C2)(OCC)OCC

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 3/20 0.40
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
HTT P42858 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29859662 0.95 ALDH1A1 (0.39) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL200331 0.90 KDM4E (0.41) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL28301327 0.88 ALDH1A1 (0.40) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL1477235 0.84 KDM4E (0.38) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL5701743 0.81 ALDH1A1 (0.37) ALDH1A1KDM4EMEN1KMT2A
SCHEMBL1878286 0.80 KDM4E (0.44) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL949256 0.79 KDM4E (0.37) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL6064281 0.79 KDM4E (0.41) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL6063180 0.79 KDM4E (0.41) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL13226801 0.78 KDM4E (0.33) ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1364975-B1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR CORP (JP) 2008-04-30 EP disclosed
US-20070225461-A1 Olefin polymers for imaging members LEXMARK INTERNATIONAL INC. 2007-09-27 US disclosed
US-20070112158-A1 Novel (co)polymer, process for producing the same, and process for producing carboxylated (co)polymer JSR CORPORATION (JP) 2007-05-17 US disclosed
EP-1686139-A1 NOVEL (CO)POLYMER, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING CARBOXYLATED (CO)POLYMER JSR Corporation (JP) 2006-08-02 EP disclosed
US-6911507-B2 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2005-06-28 US disclosed
US-20040063873-A1 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2004-04-01 US disclosed
EP-1364975-A1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR Corporation (JP) 2003-11-26 EP disclosed