Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 3/20 | 0.56 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.42 |
| ▸ | GPR52 | Q9Y2T5 | 7/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | TPH1 | P17752 | 1/20 | 0.40 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37797 | 0.87 | PDE5A (0.72) | PDE5ACDC7CCNE1CDK2ROCK1 | |
| SCHEMBL10083476 | 0.82 | PDE5A (0.51) | PDE5ACDC7CCNE1CDK2ROCK1 | |
| SCHEMBL46456 | 0.81 | PDE5A (0.57) | PDE5ACDC7CCNE1CDK2ROCK1 | |
| SCHEMBL37583 | 0.74 | PDE5A (0.78) | PDE5ACDC7CCNE1CDK2ROCK1 | |
| SCHEMBL10083509 | 0.74 | PDE5A (0.58) | PDE5ACDC7CCNE1CDK2ROCK1 | |
| SCHEMBL38065 | 0.74 | PDE5A (0.77) | PDE5ACDC7CCNE1CDK2ROCK1 | |
| SCHEMBL4520486 | 0.74 | PDE5A (0.56) | PDE5AGPR52KMT2A | |
| SCHEMBL3493412 | 0.73 | PDE5A (0.72) | PDE5AGPR52KMT2A | |
| SCHEMBL37513 | 0.73 | PDE5A (0.79) | PDE5ACDC7CCNE1CDK2ROCK1 | |
| SCHEMBL405695 | 0.72 | PDE5A (0.72) | PDE5AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004900-A1 | THIENOPYRIMIDINE COMPOUNDS | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2012-01-12 | — | — | WO | disclosed |