Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604440 | 0.84 | MAOB (0.44) | MAOBPDE4BCYP2B6ELANEACHE | |
| SCHEMBL4240828 | 0.79 | TAS1R3 (0.64) | CYP2B6ALDH1A1TAS1R3TAS1R1KDM4E | |
| SCHEMBL4247590 | 0.79 | TAS1R3 (0.64) | CYP2B6ALDH1A1TAS1R3TAS1R1KDM4E | |
| SCHEMBL4248628 | 0.79 | TAS1R3 (0.64) | CYP2B6ALDH1A1TAS1R3TAS1R1KDM4E | |
| SCHEMBL4244077 | 0.77 | PDE4A (0.46) | PDE4BCYP2B6ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL4603740 | 0.77 | TAS1R3 (0.34) | MAOBTAS1R3TAS1R1TSHRSIGMAR1 | |
| SCHEMBL4241497 | 0.77 | TAS1R3 (0.61) | CYP2B6ALDH1A1TAS1R3TAS1R1KDM4E | |
| SCHEMBL4240861 | 0.77 | HPGD (0.50) | MAOBPDE4BCYP2B6ALDH1A1NPC1 | |
| SCHEMBL4248917 | 0.77 | KMT2A (0.55) | PDE4BCYP2B6ALDH1A1ACHENPC1 | |
| SCHEMBL4248772 | 0.76 | KMT2A (0.57) | CYP2B6ALDH1A1NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940780-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049728-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | WO | disclosed |