Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4603967 | 0.79 | MAOA (0.34) | MAOAMAOB | |
| SCHEMBL4246193 | 0.77 | TAS1R3 (0.58) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4246190 | 0.77 | TAS1R3 (0.58) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4247030 | 0.77 | TAS1R3 (0.58) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4603140 | 0.77 | MAOB (0.43) | TAS1R3TAS1R1SIGMAR1TSHRMAOB | |
| SCHEMBL2282332 | 0.77 | TAS1R3 (0.41) | TAS1R3TAS1R1TAS1R2MAPK14 | |
| SCHEMBL4242303 | 0.76 | TAS1R3 (0.42) | TAS1R3TAS1R1TAS1R2MAPK14 | |
| SCHEMBL4246293 | 0.76 | TDP1 (0.39) | TAS1R3TAS1R1TAS1R2TDP1KMT2A | |
| SCHEMBL4242205 | 0.75 | TAS1R3 (0.55) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4602859 | 0.74 | RIPK1 (0.33) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940780-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049728-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | WO | disclosed |