Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4603140 | 0.84 | MAOB (0.43) | MAOBPDE4BCYP2B6ELANEACHE | |
| SCHEMBL4242863 | 0.79 | CYP2B6 (0.49) | CYP2B6ACHEMEN1KMT2ANPC1 | |
| SCHEMBL4245835 | 0.77 | MAPK14 (0.51) | PDE4BCYP2B6POLB | |
| SCHEMBL4601675 | 0.76 | SLC6A5 (0.47) | MAOBPDE4BCYP2B6ELANEACHE | |
| SCHEMBL2286794 | 0.74 | TSHR (0.68) | MAOBPDE4BCYP2B6TSHRMAPK1 | |
| SCHEMBL12799701 | 0.74 | MAOB (0.63) | MAOBPDE4BCYP2B6ACHETSHR | |
| Hydrochloric Acid SCHEMBL4252982 | 0.73 | TSHR (0.66) | MAOBPDE4BCYP2B6TSHRMAPK1 | |
| SCHEMBL2286198 | 0.73 | CYP2B6 (0.54) | MAOBPDE4BCYP2B6ACHETSHR | |
| SCHEMBL668221 | 0.73 | MAPT (0.59) | MAOBPDE4BCYP2B6TSHRMAPK1 | |
| SCHEMBL4240861 | 0.73 | HPGD (0.50) | MAOBPDE4BCYP2B6POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940780-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049728-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | WO | disclosed |