Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10404435 | 0.70 | MEN1 (0.45) | KDM4ENR1H2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL23147058 | 0.69 | ALDH1A1 (0.49) | KDM4ENR1H2NR1H3LMNASMN1; SMN2 | |
| SCHEMBL23498573 | 0.68 | SMN1; SMN2 (0.68) | KDM4ENR1H2NR1H3LMNASMN1; SMN2 | |
| SCHEMBL15413118 | 0.68 | KMT2A (0.54) | KDM4ELMNAALDH1A1CA12CA1 | |
| SCHEMBL26601966 | 0.66 | LMNA (0.56) | KDM4ELMNASMN1; SMN2KDM5AKDM5B | |
| SCHEMBL16386608 | 0.66 | ALDH1A1 (0.57) | KDM4ENR1H2NR1H3LMNASMN1; SMN2 | |
| SCHEMBL3849702 | 0.66 | PDE4D (0.64) | KDM4ENR1H2NR1H3LMNAKDM5A | |
| SCHEMBL1061985 | 0.66 | KDM4E (0.72) | KDM4ENR1H2NR1H3LMNASMN1; SMN2 | |
| SCHEMBL4751143 | 0.65 | CA12 (0.56) | KDM4ENR1H2NR1H3LMNASMN1; SMN2 | |
| SCHEMBL4273200 | 0.65 | ATAD2 (0.44) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915365-A2 | CARBOXAMIDE COMPOUND AND USE OF THE SAME | Sumitomo Chemical Company, Limited (JP) | 2008-04-30 | — | — | EP | disclosed |
| EP-1902047-A2 | CARBOXAMIDE COMPOUND AND USE OF THE SAME | Sumitomo Chemical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007007905-A2 | CARBOXAMIDE COMPOUND AND USE OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-01-18 | — | — | WO | disclosed |
| WO-2007007903-A2 | CARBOXAMIDE COMPOUND AND USE OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-01-18 | — | — | WO | disclosed |