Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13780476 | 0.82 | CA1 (0.56) | CA2CA1ALDH1A1CYP2A6SMN1; SMN2 | |
| SCHEMBL3403576 | 0.76 | CA2 (0.52) | CA2CA1ALDH1A1CYP2A6SMN1; SMN2 | |
| SCHEMBL91157 | 0.74 | CYP2A6 (0.67) | CA2CA1ALDH1A1CYP2A6SMN1; SMN2 | |
| SCHEMBL8290973 | 0.73 | CYP2A6 (0.60) | CA2CA1ALDH1A1CYP2A6SMN1; SMN2 | |
| SCHEMBL22917056 | 0.72 | ALDH1A1 (0.57) | CA2CA1ALDH1A1CYP2A6SMN1; SMN2 | |
| SCHEMBL4277592 | 0.72 | CA2 (0.45) | CA2CA1ALDH1A1CYP2A6SMN1; SMN2 | |
| SCHEMBL31111804 | 0.71 | ALDH1A1 (0.47) | CA2ALDH1A1 | |
| SCHEMBL23032558 | 0.70 | ALDH1A1 (0.54) | ALDH1A1CYP2A6SMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL1273504 | 0.70 | CYP2A6 (0.56) | CA2CA1ALDH1A1CYP2A6SMN1; SMN2 | |
| SCHEMBL4243562 | 0.70 | CA2 (1.00) | CA2CA1CYP2A6CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794143-B1 | NOVEL BENZO-FUSED HETEROARYL SULFAMIDE DERIVATIVES USEFUL AS ANTICONVULSANT AGENTS | JANSSEN PHARMACEUTICA NV (BE) | 2008-07-09 | — | — | EP | claimed |