Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PER2 | O15055 | 1/20 | 0.42 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.42 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20404472 | 0.75 | TAS2R14 (0.73) | ALDH1A1TAS2R14LMNA | |
| SCHEMBL4603299 | 0.71 | CA2 (0.54) | ALDH1A1CA2 | |
| SCHEMBL12124983 | 0.71 | KDM4E (0.57) | ALDH1A1RIPK1GAAKDM4EAOC3 | |
| SCHEMBL29943841 | 0.69 | — | — | |
| SCHEMBL138361 | 0.69 | — | — | |
| SCHEMBL27390411 | 0.69 | TAAR1 (0.53) | ALDH1A1RECQLRIPK1KDM4EAOC3 | |
| SCHEMBL30409980 | 0.69 | LMNA (0.52) | ALDH1A1CA2RECQLGAALMNA | |
| SCHEMBL51098 | 0.69 | LMNA (0.52) | ALDH1A1CA2RECQLGAALMNA | |
| SCHEMBL18884417 | 0.69 | AOC3 (0.66) | ALDH1A1RECQLRIPK1GAAKDM4E | |
| SCHEMBL10561470 | 0.68 | TAS2R14 (0.48) | ALDH1A1TAS2R14RECQLHTTPER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024227104-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BRAF VIA UBIQUITIN PROTEOSOME PATHWAY | NURIX THERAPEUTICS, INC. (US) | 2024-10-31 | — | — | WO | disclosed |