Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14540913 | 0.76 | PTPRC (0.38) | MAPTKDM4ESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9732679 | 0.74 | HKDC1 (0.39) | MAPTKDM4ESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL181251 | 0.67 | — | — | |
| SCHEMBL14318236 | 0.67 | KDM4E (0.49) | MAPTKDM4ESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL13698243 | 0.65 | — | — | |
| SCHEMBL1163613 | 0.65 | — | — | |
| SCHEMBL11375720 | 0.63 | GSK3A (0.38) | MAPTKDM4ESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL49737 | 0.62 | ERBB2 (0.62) | MAPTKDM4ESMN1; SMN2ALDH1A1HKDC1 | |
| SCHEMBL3417111 | 0.62 | HKDC1 (0.56) | MAPTKDM4ESMN1; SMN2ALDH1A1HKDC1 | |
| SCHEMBL15906750 | 0.62 | MAPT (0.39) | MAPTKDM4ESMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940390-A2 | ANTIBACTERIAL PYRROLS | Aston University (GB) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007039749-A2 | ANTIBACTERIAL PYRROLS | ASTON UNIVERSITY (GB) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007039749-A2 | ANTIBACTERIAL PYRROLS | ASTON UNIVERSITY (GB) | 2007-04-12 | — | — | WO | disclosed |