⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181251 | 0.70 | — | — | |
| SCHEMBL14136363 | 0.69 | ALDH1A1 (0.46) | — | |
| SCHEMBL1163613 | 0.68 | — | — | |
| SCHEMBL19886759 | 0.68 | MGLL (0.46) | — | |
| SCHEMBL11375720 | 0.67 | GSK3A (0.38) | — | |
| SCHEMBL14318236 | 0.65 | KDM4E (0.49) | — | |
| SCHEMBL4603359 | 0.65 | MAPT (0.49) | — | |
| SCHEMBL15906750 | 0.65 | MAPT (0.39) | — | |
| SCHEMBL14314260 | 0.65 | MGLL (0.36) | — | |
| SCHEMBL23052619 | 0.64 | GSK3A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3429558-B1 | FUMARATE POLYMERSOMES | UCL BUSINESS LTD (GB) | 2023-06-07 | — | — | EP | disclosed |
| US-11485792-B2 | Antibodies, uses thereof and conjugates thereof | POLYTHERICS LIMITED | 2022-11-01 | — | — | US | disclosed |
| US-20220193249-A1 | Conjugates And Conjugating Reagents Comprising A Linker That Includes At Least Two (-CH2-CH2-O-) Units In A Ring | POLYTHERICS LIMITED (GB) | 2022-06-23 | — | — | US | disclosed |
| US-11059903-B2 | Anti-PSMA antibodies, uses thereof and conjugates thereof | POLYTHERICS LIMITED (GB) | 2021-07-13 | — | — | US | disclosed |
| EP-3159737-B1 | LIQUID CRYSTAL DISPLAY ELEMENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL ALIGNMENT TREATMENT AGENT | NISSAN CHEMICAL CORP (JP) | 2021-05-26 | — | — | EP | disclosed |
| US-10835616-B2 | Process for the conjugation of a peptide or protein with a reagent comprising a leaving group including a portion of PEG | POLYTHERICS LIMITED (GB) | 2020-11-17 | — | — | US | disclosed |
| US-10654873-B2 | Cytotoxic agents and conjugates thereof | POLYTHERICS LIMITED (GB) | 2020-05-19 | — | — | US | disclosed |
| US-20190328893-A1 | Conjugates And Conjugating Reagents Comprising A Linker That Includes At Least Two (-CH2-CH2-0-) Units In A Ring | POLYTHERICS LIMITED (GB) | 2019-10-31 | — | — | US | disclosed |
| US-20190300623-A1 | ANTI-PSMA ANTIBODIES, USES THEREOF AND CONJUGATES THEREOF | ABZENA (UK) LIMITED (GB) | 2019-10-03 | — | — | US | disclosed |
| US-10386681-B2 | Liquid crystal display element | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2019-08-20 | — | — | US | disclosed |
| US-20190144562-A1 | ANTIBODIES, USES THEREOF AND CONJUGATES THEREOF | ABZENA (UK) LIMITED (GB) | 2019-05-16 | — | — | US | disclosed |
| US-20180015180-A1 | SHORT AND D-AMINO ACID-CONTAINING POLYPEPTIDES FOR THERAPEUTIC CONJUGATES AND USES THEREOF | ANGIOCHEM INC (CA) | 2018-01-18 | — | — | US | disclosed |
| US-20170326233-A1 | CONJUGATES INCLUDING AN ANTIBODY MOIETY, A POLYPEPTIDE THAT TRAVERSES THE BLOOD-BRAIN BARRIER, AND A CYTOTOXIN | ANGIOCHEM INC (CA) | 2017-11-16 | — | — | US | disclosed |
| US-20170304461-A1 | Process For The Conjugation Of A Peptide Or Protein With A Reagent Comprising A Leaving Group Including A Portion Of PEG | POLYTHERICS LIMITED (GB) | 2017-10-26 | — | — | US | disclosed |
| US-20170281787-A1 | CONJUGATES INCLUDING AN ANTIBODY MOIETY, A POLYPEPTIDE THAT TRAVERSES THE BLOOD-BRAIN BARRIER, AND A CYTOTOXIN | ANGIOCHEM INC (CA) | 2017-10-05 | — | — | US | disclosed |
| EP-3217212-A1 | LIQUID CRYSTAL DISPLAY ELEMENT | Nissan Chemical Industries, Ltd. (JP) | 2017-09-13 | — | — | EP | disclosed |
| US-20170199434-A1 | LIQUID CRYSTAL DISPLAY ELEMENT | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-07-13 | — | — | US | disclosed |
| US-20170184923-A1 | LIQUID CRYSTAL DISPLAY ELEMENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL ALIGNMENT TREATMENT AGENT | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-06-29 | — | — | US | disclosed |
| US-9687561-B2 | Peptide-dendrimer conjugates and uses thereof | ANGIOCHEM INC. (CA) | 2017-06-27 | — | — | US | disclosed |
| US-20090233978-A1 | Novel 1-Aryl-3-Azabicyclo[3.1.0]Hexanes: Preparation And Use To Treat Neuropsychiatric Disorders | OTSUKA AMERICA PHARMACEUTICAL, INC. | 2009-09-17 | — | — | US | disclosed |