P-Xylene

P-Xylene

SCHEMBL1508153

Cc1ccc(C)cc1.Cc1ccc(C)cc1.Cc1ccc(C)cc1.Cc1ccc(C)cc1.Cc1ccc(C)cc1.Cc1ccc(C)cc1.F.F.F.F.F.F

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.89
TDP1 Q9NUW8 1/20 0.89
ALDH1A1 P00352 4/20 0.57
CA2 P00918 2/20 0.57
CA1 P00915 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
TSHR P16473 3/20 0.54
LMNA P02545 2/20 0.54
ALOX12 P18054 1/20 0.54
CYP2A6 P11509 3/20 0.47
IDO1 P14902 1/20 0.47
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
LPL P06858 1/20 0.47
LIPG Q9Y5X9 1/20 0.47
ORAI1 Q96D31 1/20 0.47
ORAI2 Q96SN7 1/20 0.47
ORAI3 Q9BRQ5 1/20 0.47
TRPV6 Q9H1D0 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Xylene SCHEMBL1508156 1.00 ACHE (0.89) ACHETDP1ALDH1A1CA2CA1
P-Xylene SCHEMBL8379949 1.00
P-Xylene SCHEMBL27682563 1.00 ACHE (0.89) ACHETDP1ALDH1A1CA2CA1
P-Xylene SCHEMBL28512884 1.00 ACHE (0.89) ACHETDP1ALDH1A1CA2CA1
P-Xylene SCHEMBL9195031 0.95 ACHE (0.80) ACHETDP1ALDH1A1CA2CA1
P-Xylene SCHEMBL11772917 0.94 ACHE (1.00) ACHETDP1ALDH1A1CA2CA1
P-Xylene SCHEMBL771 0.94
P-Xylene SCHEMBL11770184 0.94 ACHE (1.00) ACHETDP1ALDH1A1CA2CA1
P-Xylene SCHEMBL460348 0.94 ACHE (1.00) ACHETDP1ALDH1A1CA2CA1
P-Xylene SCHEMBL180004 0.89 ACHE (0.89) ACHETDP1ALDH1A1CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3088487-B1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND DAIKIN IND LTD (JP) 2021-05-05 EP claimed
US-10703932-B2 Surface treating agent including perfluoro(poly)ether-group-containing silane compound DAIKIN INDUSTRIES, LTD. (JP) 2020-07-07 US claimed
US-20160340544-A1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2016-11-24 US claimed
EP-3088487-A1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND Daikin Industries, Ltd. (JP) 2016-11-02 EP claimed
EP-3088487-B1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND DAIKIN IND LTD (JP) 2021-05-05 EP disclosed
US-10703932-B2 Surface treating agent including perfluoro(poly)ether-group-containing silane compound DAIKIN INDUSTRIES, LTD. (JP) 2020-07-07 US disclosed
US-20160340544-A1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2016-11-24 US disclosed
EP-3088487-A1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND Daikin Industries, Ltd. (JP) 2016-11-02 EP disclosed
EP-2468778-B1 FLUOROALKYL GROUP-CONTAINING N-SUBSTITUTED (METH)ACRYLAMIDE COMPOUND, POLYMER THEREOF, AND USE THEREOF AGC SEIMI CHEMICAL CO LTD (JP) 2016-10-12 EP disclosed
US-9000110-B2 Fluoroalkyl group-containing n-substituted (meth)acrylamide compound, polymer thereof, and use thereof AGC SEIMI CHEMICAL CO., LTD. (JP) 2015-04-07 US disclosed
US-8865820-B2 Fluorine-containing curable composition and rubber article SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-10-21 US disclosed
US-8835549-B2 Coating composition for engine parts and engine part comprising it KABUSHIKI KAISHA RIKEN (JP) 2014-09-16 US disclosed
US-20110060109-A1 RT CURABLE FLUOROPOLYETHER BASE RUBBER COMPOSITION AND CURED PRODUCT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-03-10 US disclosed
US-RE40519-E1 Conductive fluoro-resin compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-09-23 US disclosed
US-7182881-B2 Fire extinguishing agent and fire extinguisher KABUSHIKI KAISHA TOSHIBA (JP) 2007-02-27 US disclosed
US-20040118576-A1 Fire extinguishing agent and fire extinguisher KABUSHIKI KAISHA TOSHIBA (JP) 2004-06-24 US disclosed
EP-0923084-B1 Conductive fluoro-resin compositions SHINETSU CHEMICAL CO (JP) 2003-03-26 EP disclosed
US-6121359-A COMPRISING SILVER PARTICLES, WHICH HAVE BEEN SURFACE TREATED BY COUPLING WITH A SILICON COMPOUND AND HYDROSILATION WITH FLUORINATED POLYETHER; DIE BONDING OF SEMICONDUCTOR DEVICES AND MOUNTING OF QUARTZ CRYSTAL OSCILLATORS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-09-19 US disclosed
EP-0923084-A1 Conductive fluoro-resin compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-06-16 EP disclosed
US-5141991-A Vulcanizing with at least one organosilicon compound or polysilixanes SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10703932-B2 Surface treating agent including perfluoro(poly)ether-group-containing silane compound FRG1, AFF1, F11 ACHE 4608/4885TDP1 3197/4885ALDH1A1 1578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.