SCHEMBL460366

SCHEMBL460366

Cc1cc(Br)c2ccc3c(Br)cc(C)nc3c2n1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.44
RAB9A P51151 1/20 0.44
CCR5 P51681 1/20 0.44
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 3/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 5/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TDP1 Q9NUW8 1/20 0.38
GAA P10253 2/20 0.38
MAPK1 P28482 1/20 0.38
OPRK1 P41145 1/20 0.36
NR4A2 P43354 1/20 0.36
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26130986 0.92 CCR1 (0.60) CCR1RAB9ACCR5KDM4EALDH1A1
SCHEMBL31191929 0.92 CCR1 (0.60) CCR1RAB9ACCR5KDM4EALDH1A1
SCHEMBL4586663 0.83 CCR1 (0.60) CCR1RAB9ACCR5KDM4EALDH1A1
SCHEMBL7219924 0.81 TP53 (0.54) RAB9AKDM4EALDH1A1KMT2AMEN1
SCHEMBL1563032 0.78 METAP2 (0.55) KDM4EKMT2AMEN1MAPTL3MBTL1
SCHEMBL11626595 0.78 KDM4E (0.69) RAB9AKDM4EALDH1A1KMT2AMEN1
SCHEMBL16506398 0.78 KDM4E (0.42) KDM4EKMT2AMEN1MAPTL3MBTL1
SCHEMBL30018810 0.76 ALDH1A1 (0.43) KDM4EALDH1A1KMT2AMEN1MAPT
SCHEMBL1563307 0.76 GFER (0.50) RAB9AKDM4EALDH1A1MAPTGAA
Broquinaldol SCHEMBL29606314 0.76 MAPT (0.54) CCR1RAB9ACCR5KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117447516-A 4-pyridyl modified copper (I) metal complex and preparation method and application thereof 中山大学 2024-01-26 CN disclosed
US-11839154-B2 Phenanthroline-based compound and optoelectronic device comprising the same GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY 2023-12-05 US disclosed
US-11839154-B2 Phenanthroline-based compound and optoelectronic device comprising the same GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY 2023-12-05 US disclosed
US-11839154-B2 Phenanthroline-based compound and optoelectronic device comprising the same GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY 2023-12-05 US disclosed
US-20230255108-A1 NOVEL PHENANTHROLINE-BASED COMPOUND AND OPTOELECTRONIC DEVICE COMPRISING THE SAME GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-08-10 US disclosed
US-20230255108-A1 NOVEL PHENANTHROLINE-BASED COMPOUND AND OPTOELECTRONIC DEVICE COMPRISING THE SAME GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-08-10 US disclosed
US-20230255108-A1 NOVEL PHENANTHROLINE-BASED COMPOUND AND OPTOELECTRONIC DEVICE COMPRISING THE SAME GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-08-10 US disclosed
EP-4223744-A1 NOVEL PHENANTHROLINE-BASED COMPOUND AND OPTOELECTRONIC DEVICE COMPRISING THE SAME Gwangju Institute of Science and Technology (KR) 2023-08-09 EP disclosed
EP-4223744-A1 NOVEL PHENANTHROLINE-BASED COMPOUND AND OPTOELECTRONIC DEVICE COMPRISING THE SAME Gwangju Institute of Science and Technology (KR) 2023-08-09 EP disclosed
EP-2595997-B1 COPPER(I) COMPLEXES FOR OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2015-09-16 EP disclosed
EP-2595997-B1 COPPER(I) COMPLEXES FOR OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2015-09-16 EP disclosed
US-9024026-B2 Copper (I) complexes for optoelectronic devices CYNORA GMBH (DE) 2015-05-05 US disclosed
US-9024026-B2 Copper (I) complexes for optoelectronic devices CYNORA GMBH (DE) 2015-05-05 US disclosed
US-9024026-B2 Copper (I) complexes for optoelectronic devices CYNORA GMBH (DE) 2015-05-05 US disclosed
US-20130150581-A1 COPPER (I) COMPLEXES FOR OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2013-06-13 US disclosed
US-20130150581-A1 COPPER (I) COMPLEXES FOR OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2013-06-13 US disclosed
US-20130150581-A1 COPPER (I) COMPLEXES FOR OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2013-06-13 US disclosed
EP-2595997-A1 COPPER (I) COMPLEXES FOR OPTOELECTRONIC DEVICES Cynora GmbH (DE) 2013-05-29 EP disclosed
WO-2012010650-A1 COPPER (I) COMPLEXES FOR OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2012-01-26 WO disclosed
WO-2012010650-A1 COPPER (I) COMPLEXES FOR OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2012-01-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839154-B2 Phenanthroline-based compound and optoelectronic device comprising the same PAH, PPOX, HCN2 CCR1 2972/4885RAB9A 1965/4885CCR5 2095/4885
US-20230255108-A1 NOVEL PHENANTHROLINE-BASED COMPOUND AND OPTOELECTRONIC DEVICE COMPRISING THE SAME PAH, PPOX, ODC1 CCR1 2613/4885RAB9A 1650/4885CCR5 1900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.