SCHEMBL4603820

SCHEMBL4603820

Cc1ccc(S(=O)(=O)ON(C(N)=O)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46
ALDH1A1 P00352 6/20 0.45
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
GAA P10253 1/20 0.44
PPARG P37231 1/20 0.40
VDR P11473 1/20 0.40
RECQL P46063 1/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
PTGES O14684 1/20 0.39
LMNA P02545 2/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C19 P33261 1/20 0.38
F2 P00734 1/20 0.38
PRSS1 P07477 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25368288 0.85 CA12 (0.43) CA12CA9ALDH1A1KMT2AMEN1
SCHEMBL29113141 0.84 RECQL (0.46) CA12CA9ALDH1A1KMT2AMEN1
SCHEMBL28620341 0.81 LMNA (0.50) CA12CA9ALDH1A1KMT2AMEN1
SCHEMBL6315850 0.79 CA12 (0.56) CA12CA9ALDH1A1KMT2AMEN1
SCHEMBL28218283 0.78 NR3C2 (0.39) ALDH1A1KMT2AMEN1SMN1; SMN2LMNA
SCHEMBL14620608 0.76 ALDH1A1 (0.53) ALDH1A1KMT2AMEN1GAASMN1; SMN2
SCHEMBL27561911 0.76 CA1 (0.39) CA12CA9ALDH1A1KMT2AMEN1
SCHEMBL25416632 0.75 ALDH1A1 (0.47) ALDH1A1KMT2AMEN1GAAMAPT
SCHEMBL25416636 0.74 HTR6 (0.45) ALDH1A1KMT2AMEN1HTTSMN1; SMN2
SCHEMBL1878018 0.74 CA12 (0.58) CA12CA9ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1940629-A1 IMAGE RECORDING MEDIA AND IMAGE LAYERS Hewlett-Packard Development Company, L.P. (US) 2008-07-09 EP disclosed
WO-2007050457-A1 IMAGE RECORDING MEDIA AND IMAGE LAYERS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2007-05-03 WO disclosed
US-6784136-B2 RECORDING LAYER OF A FLUORAN BASED LEUCO DYE WITH MELTING POINT OF 190-230 DEGREES C AND N-P-TOLUENESULFONYL-N'-3-(P-TOLUENESULFONYLOXY) PHENYLUREA DEVELOPER, AND ALUMINUM HYDROXIDE, AMORPHOUS SILICA, KAOLIN OR TALC AS PIGMENTS OJI PAPER CO., LTD. (JP) 2004-08-31 US disclosed