Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | HTT | P42858 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602685 | 0.87 | TDP1 (0.45) | KMT2AHTTMEN1MAPTKDM4E | |
| SCHEMBL5850441 | 0.86 | MAPT (0.41) | KMT2AHTTMEN1MAPTKDM4E | |
| SCHEMBL15600148 | 0.84 | KMT2A (0.58) | KMT2AHTTMEN1MAPTKDM4E | |
| SCHEMBL5850948 | 0.83 | MPI (0.40) | KMT2AHTTMEN1MAPTKDM4E | |
| SCHEMBL9750440 | 0.82 | GRIA2 (0.42) | KMT2AHTTMEN1MAPTKDM4E | |
| SCHEMBL4603122 | 0.80 | MPI (0.50) | KMT2AHTTMEN1MAPTKDM4E | |
| SCHEMBL3809912 | 0.80 | POLB (0.43) | KMT2AHTTMEN1MAPTKDM4E | |
| SCHEMBL4604095 | 0.80 | MPI (0.43) | KMT2AHTTMEN1MAPTKDM4E | |
| SCHEMBL31318038 | 0.80 | MPI (0.43) | KMT2AHTTMEN1MAPTKDM4E | |
| SCHEMBL4602881 | 0.80 | MPI (0.43) | KMT2AHTTMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194633-B1 | AGENT FOR COLORING FIBERS AND METHOD FOR TEMPORARILY COLORING FIBERS | WELLA AG (DE) | 2008-04-30 | — | — | EP | claimed |
| EP-1341503-B1 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2008-02-13 | — | — | EP | claimed |
| EP-1227786-B1 | AGENT FOR DYEING FIBRES COMPRISING AN INDOLINE/INDOLIUM DERIVATIVE | WELLA AG (DE) | 2005-08-24 | — | — | EP | claimed |
| US-6835212-B2 | Compound with a nucleophilic reaction center, aryl alcohol or benzyl alcohol derivatives and an oxidizing enzyme | WELLA AKTIENGESELLSCHAFT (DE) | 2004-12-28 | — | — | US | claimed |
| EP-1194118-B1 | AGENT FOR COLORING FIBERS | WELLA AG (DE) | 2004-09-15 | — | — | EP | claimed |
| US-6740128-B2 | BLEND CONTAINING ENAMINE AND ALKALINE MIXTURE OF ALDEHYDE AND PRIMARY AMINE | WELLA AKTIENGESELLSCHAFT (DE) | 2004-05-25 | — | — | US | claimed |
| US-6669739-B2 | Agent for coloring fibers and method for temporarily coloring fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2003-12-30 | — | — | US | claimed |
| US-6652601-B2 | For dyeing and subsequently decolorizing fibers such as keratin fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2003-11-25 | — | — | US | claimed |
| US-20030101520-A1 | Agent for coloring fibers | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-06-05 | — | — | US | claimed |
| US-20030079301-A1 | Agent for dyeing fibers comprising an indoline/indolium derivative | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-05-01 | — | — | US | claimed |
| US-20030041391-A1 | Agent and method for dyeing keratin fibres | Wella GmbH (DE) | 2003-03-06 | — | — | US | claimed |
| US-20020172651-A1 | Agent for coloring fibers and method for temporarily coloring fibers | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2002-11-21 | — | — | US | claimed |
| JP-6287210-A | — | — | None | — | — | JP | disclosed |
| EP-3632443-B1 | ANTI-TUMOR EFFECT POTENTIATOR USING A BIPHENYL COMPOUND | TAIHO PHARMACEUTICAL CO LTD (JP) | 2023-06-07 | — | — | EP | disclosed |
| CN-111440193-B | Indene-thick naphtho-spirooxazine photochromic compound and preparation method thereof | 南开大学 | 2023-01-24 | — | — | CN | disclosed |
| CN-111440193-A | Indene-thick naphtho-spirooxazine photochromic compound and preparation method thereof | 南开大学 | 2020-07-24 | — | — | CN | disclosed |
| US-4201707-A | Methine dyestuffs containing a phenyl azo group | BAYER AKTIENGESELLSCHAFT (DE) | 1980-05-06 | — | — | US | disclosed |
| US-4143228-A | RED SHADES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-06 | — | — | US | disclosed |
| US-4138570-A | METHINE DYE | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-06 | — | — | US | disclosed |
| US-3944556-A | PHOTOCONDUCTOR, FLUORESCENT, PHOTOGRAPHY | FUJI PHOTO FILM CO., LTD. (JA) | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030079301-A1 | Agent for dyeing fibers comprising an indoline/indolium derivative | IDO1, IDO2, KIT | KMT2A 719/4885HTT 2640/4885MEN1 1860/4885 |
| US-20030101520-A1 | Agent for coloring fibers | COL1A1, ENO1, H1-5 | KMT2A 1390/4885HTT 2080/4885MEN1 996/4885 |
| US-20020172651-A1 | Agent for coloring fibers and method for temporarily coloring fibers | ENO1, H1-5, H1-2 | KMT2A 943/4885HTT 2325/4885MEN1 1144/4885 |
| US-20030041391-A1 | Agent and method for dyeing keratin fibres | KRT18, AKR7A2, ADH5 | KMT2A 651/4885HTT 4139/4885MEN1 4837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.