Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 6/20 | 0.35 |
| ▸ | CNR2 | P34972 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602830 | 0.96 | HPGD (0.44) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4603892 | 0.96 | HPGD (0.41) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4603936 | 0.84 | ALDH1A1 (0.49) | HPGDRAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL4602096 | 0.84 | ALDH1A1 (0.46) | HPGDRAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL4602234 | 0.81 | KDM4E (0.45) | RAB9ASMN1; SMN2POLBALDH1A1CNR1 | |
| SCHEMBL4603249 | 0.81 | HTR2A (0.41) | HPGDPOLBALDH1A1CNR1CNR2 | |
| SCHEMBL4244880 | 0.78 | MAPK14 (0.42) | HPGDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4603541 | 0.78 | ALDH1A1 (0.48) | HPGDRAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL4602587 | 0.77 | HPGD (0.42) | HPGDNPC1RAB9APOLBALDH1A1 | |
| SCHEMBL4603506 | 0.77 | HPGD (0.45) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940780-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049728-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | WO | disclosed |