SCHEMBL4603893

SCHEMBL4603893

F[Si](F)(F)C1CC2C=CC1C2

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3267075 0.80 KDM4E (0.33) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL16773667 0.80 KDM4E (0.33) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL4266840 0.76 KDM4E (0.39) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL4602316 0.75 KDM4E (0.33) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL200641 0.75 KDM4E (0.38) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL6697237 0.73 KDM4E (0.37) KDM4EALDH1A1
SCHEMBL6693469 0.73 KDM4E (0.37) KDM4EALDH1A1
SCHEMBL201850 0.72 KDM4E (0.36) KDM4EALDH1A1
SCHEMBL202350 0.72 KDM4E (0.36) KDM4EALDH1A1
SCHEMBL200393 0.71 KDM4E (0.32) KDM4ELMNAALDH1A1GAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1364975-B1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR CORP (JP) 2008-04-30 EP disclosed
US-20070225461-A1 Olefin polymers for imaging members LEXMARK INTERNATIONAL INC. 2007-09-27 US disclosed
US-20070112158-A1 Novel (co)polymer, process for producing the same, and process for producing carboxylated (co)polymer JSR CORPORATION (JP) 2007-05-17 US disclosed
EP-1686139-A1 NOVEL (CO)POLYMER, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING CARBOXYLATED (CO)POLYMER JSR Corporation (JP) 2006-08-02 EP disclosed
US-6911507-B2 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2005-06-28 US disclosed
US-20040063873-A1 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2004-04-01 US disclosed
EP-1364975-A1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR Corporation (JP) 2003-11-26 EP disclosed