SCHEMBL3267075

SCHEMBL3267075

C[Si](C)(C)C1CC2C=CC1C2

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6904497 0.86 KDM4E (0.35) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL6836633 0.81 KDM4E (0.35) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL200393 0.81 KDM4E (0.32) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL6902908 0.81 KDM4E (0.32) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL4603893 0.80 KDM4E (0.33) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL6063967 0.79 KDM4E (0.31) KDM4EALDH1A1LMNA
SCHEMBL7113258 0.79 KDM4E (0.31) KDM4EALDH1A1LMNA
SCHEMBL2605522 0.78 KDM4E (0.30) KDM4EALDH1A1
SCHEMBL200055 0.78 KDM4E (0.30) KDM4EALDH1A1
SCHEMBL6063915 0.78 KDM4E (0.30) KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025038867-A1 THIN-FILM COMPOSITE MEMBRANES INCORPORATING A POLYPHENYLENE IONOMER AND SEPARATION PROCESSES THEREWITH COMPACT MEMBRANE SYSTEMS, INC. (US) 2025-02-20 WO claimed
US-20240299887-A1 THIN-FILM COMPOSITE MEMBRANES HAVING IMPROVED ADHESION BETWEEN LAYERS AND USES THEREOF U.S. DEPARTMENT OF ENERGY 2024-09-12 US claimed
EP-4370238-A1 THIN-FILM COMPOSITE MEMBRANES HAVING IMPROVED ADHESION BETWEEN LAYERS AND USES THEREOF COMPACT MEMBRANE SYSTEMS, INC. (US) 2024-05-22 EP claimed
CN-117751006-A Film composite film with improved interlayer adhesion and use thereof 卡姆帕特薄膜系统公司 2024-03-22 CN claimed
WO-2023287628-A1 THIN-FILM COMPOSITE MEMBRANES HAVING IMPROVED ADHESION BETWEEN LAYERS AND USES THEREOF COMPACT MEMBRANE SYSTEMS INC. (US) 2023-01-19 WO claimed
US-9291901-B2 Amine treated maleic anhydride polymers with pendent silyl group, compositions and applications thereof SUMITOMO BAKELITE CO., LTD. (JP) 2016-03-22 US claimed
WO-2015038412-A2 AMINE TREATED MALEIC ANHYDRIDE POLYMERS WITH PENDENT SILYL GROUP, COMPOSITIONS AND APPLICATIONS THEREOF PROMERUS, LLC (US) 2015-03-19 WO claimed
US-20150079507-A1 AMINE TREATED MALEIC ANHYDRIDE POLYMERS WITH PENDENT SILYL GROUP, COMPOSITIONS AND APPLICATIONS THEREOF PROMERUS, LLC (US) 2015-03-19 US claimed
US-20020177066-A1 Silicon-containing copolymer and photosensitive resin composition containing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2002-11-28 US claimed
US-20250313662-A1 IRON-CATALYZED METATHESIS POLYMERIZATION OF OLEFINS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2025-10-09 US disclosed
EP-4617314-A1 COMPOSITION FOR FORMING A MOLDED PRODUCT HAVING LOW DIELECTRIC LOSS, METHOD FOR FORMING A MOLDED PRODUCT, AND MOLDED PRODUCT HAVING LOW DIELECTRIC LOSS Daikin Industries, Ltd. (JP) 2025-09-17 EP disclosed
WO-2025038867-A1 THIN-FILM COMPOSITE MEMBRANES INCORPORATING A POLYPHENYLENE IONOMER AND SEPARATION PROCESSES THEREWITH COMPACT MEMBRANE SYSTEMS, INC. (US) 2025-02-20 WO disclosed
CN-119371641-A Cyclic olefin ring-opening polymer and hydride thereof 杭州睿丰融创科技有限公司 2025-01-28 CN disclosed
US-20240299887-A1 THIN-FILM COMPOSITE MEMBRANES HAVING IMPROVED ADHESION BETWEEN LAYERS AND USES THEREOF U.S. DEPARTMENT OF ENERGY 2024-09-12 US disclosed
EP-0317262-B1 Transparent resin material JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-01-31 EP disclosed
US-5164469-A Substrate for optical disks, ring opening polymerization of tetracyclododecene derivatives JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-11-17 US disclosed
US-5053471-A Methathesis ring opening polymerization of polar substituted norbornenes or octahydromethanonphthalenes; optics JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-10-01 US disclosed
EP-0409291-A2 Thermoplastic resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-01-23 EP disclosed
EP-0317262-A2 Transparent resin material JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1989-05-24 EP disclosed
US-4250063-A COORDINATION CATALYST COMPRISING AN ORGANIC COMPLEX OF TUNGSTEN OR MOLYBDENUM, A TITANIUM TETRAHALIDE, AND AN N-HALO IMIDE, A SULFIDE, A SULFOXIDE, OR A PHOSPHINE; POLYALKENAMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313662-A1 IRON-CATALYZED METATHESIS POLYMERIZATION OF OLEFINS PPOX, HMOX1, HMOX2 KDM4E 2697/4885ALDH1A1 1463/4885LMNA 4721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.