Butyric Acid

Butyric Acid

SCHEMBL4604017

CC(=O)OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O.CCCC(=O)O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
FPR2 P25090 2/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
USP2 O75604 1/20 0.32
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
RECQL P46063 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PRKCA P17252 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL4606286 0.89 LMNA (0.32) FFAR3USP2LMNACYP3A4MAPT
Butyric Acid SCHEMBL15324264 0.88 KDM4E (0.31) LMNAPRKCA
SCHEMBL426315 0.87 MPI (0.36) USP2LMNACYP3A4MAPTRECQL
SCHEMBL2884877 0.87 MPI (0.36) USP2LMNACYP3A4MAPTRECQL
SCHEMBL215097 0.87 MPI (0.36) USP2LMNACYP3A4MAPTRECQL
SCHEMBL13430949 0.87 MPI (0.36) USP2LMNACYP3A4MAPTRECQL
Butyric Acid SCHEMBL4605193 0.87 FFAR3 (0.37) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL4091036 0.86 PRKCA (0.31) FPR2NFKB1NFKB2RELAPRKCA
SCHEMBL7070578 0.82 MPI (0.37) USP2LMNACYP3A4MAPTRECQL
SCHEMBL7066959 0.82 MPI (0.37) USP2LMNACYP3A4MAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101299992-A Carboxyalkyl cellulose esters for the long-acting delivery of pharmaceutically active substances EASTMAN CHEM CO (US) 2008-11-05 CN disclosed
EP-1942869-A2 CARBOXYALKYL CELLULOSE ESTERS FOR SUSTAINED DELIVERY OF PHARMACEUTICALLY ACTIVE SUBSTANCES EASTMAN CHEMICAL COMPANY (US) 2008-07-16 EP disclosed
WO-2007056125-A2 CARBOXYALKYL CELLULOSE ESTERS FOR SUSTAINED DELIVERY OF PHARMACEUTICALLY ACTIVE SUBSTANCES EASTMAN CHEMICAL COMPANY (US) 2007-05-18 WO disclosed
US-20070104787-A1 Carboxyalkyl cellulose esters for sustained delivery of pharmaceutically active substances EASTMAN CHEMICAL COMPANY 2007-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070104787-A1 Carboxyalkyl cellulose esters for sustained delivery of pharmaceutically active substances SLC2A1, SLC2A8, SLC2A4 FFAR3 1025/4885HDAC3 1062/4885HDAC1 1982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.