Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Butyric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Demannose SCHEMBL4091029 | 0.88 | FPR2 (0.34) | FPR2NFKB1NFKB2RELA | |
| Butyric Acid SCHEMBL4604017 | 0.86 | FFAR3 (0.38) | PRKCAFPR2NFKB1NFKB2RELA | |
| Butyric Acid SCHEMBL15324264 | 0.78 | KDM4E (0.31) | PRKCA | |
| Lactic Acid SCHEMBL18423690 | 0.77 | FFAR3 (0.42) | — | |
| Propionic Acid SCHEMBL4606286 | 0.77 | LMNA (0.32) | — | |
| SCHEMBL215097 | 0.75 | MPI (0.36) | — | |
| SCHEMBL2884877 | 0.75 | MPI (0.36) | — | |
| SCHEMBL426315 | 0.75 | MPI (0.36) | — | |
| SCHEMBL13430949 | 0.75 | MPI (0.36) | — | |
| Hexadecane SCHEMBL10787942 | 0.75 | PRKCA (0.41) | PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102351-A1 | METHOD FOR PREPARING BUTANOL THROUGH BUTYRYL-COA AS AN INTERMEDIATE USING BACTERIA | Biofuelchem Co., Ltd. (KR) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008072920-A1 | METHOD FOR PREPARING BUTANOL THROUGH BUTYRYL-COA AS AN INTERMEDIATE USING BACTERIA | BIOFUELCHEM CO., LTD. (KR) | 2008-06-19 | — | — | WO | disclosed |