Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK2 | O95069 | 3/20 | 0.42 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4605316 | 0.84 | AKR1C3 (0.46) | KDM4EALDH1A1GAASMN1; SMN2MEN1 | |
| SCHEMBL4605959 | 0.84 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10IGF2BP2GAA | |
| SCHEMBL4606034 | 0.80 | IGF2BP2 (0.51) | KCNK2KCNK10KDM4EALDH1A1HSD17B10 | |
| SCHEMBL4606033 | 0.79 | RORC (0.47) | KDM4EALDH1A1HSD17B10IGF2BP2GAA | |
| SCHEMBL4604536 | 0.79 | RXRA (0.57) | KDM4EALDH1A1HSD17B10IGF2BP2GAA | |
| SCHEMBL4617063 | 0.78 | ALDH1A1 (0.41) | KDM4EALDH1A1TP53SMN1; SMN2MEN1 | |
| SCHEMBL4604809 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4604701 | 0.77 | IGF2BP2 (0.48) | KCNK2KCNK10KDM4EALDH1A1HSD17B10 | |
| SCHEMBL4604597 | 0.76 | FFAR1 (0.51) | KDM4EALDH1A1HSD17B10IGF2BP2GAA | |
| SCHEMBL4605977 | 0.76 | KDM4E (0.41) | KCNK2KCNK10KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720825-B1 | ANTHRANILIC ACID DERIVATIVES, METHODS FOR THEIR PREPARATION AND USE AS DHODH INHIBITORS | ACTIVE BIOTECH AB (SE) | 2008-07-09 | — | — | EP | disclosed |
| EP-1720825-A1 | NEW COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF | Active Biotech AB (SE) | 2006-11-15 | — | — | EP | disclosed |
| US-7074831-B2 | Compounds, methods for their preparation and use thereof | ACTIVE BIOTECH AB (SE) | 2006-07-11 | — | — | US | disclosed |
| WO-2005075410-A1 | NEW COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF | ACTIVE BIOTECH AB (SE) | 2005-08-18 | — | — | WO | disclosed |