SCHEMBL4604142

SCHEMBL4604142

C=CCn1c2ccccc2c2cc(-c3ccc4c(c3)c3ccccc3n4CC=C)ccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 6/20 0.50
ALDH1A1 P00352 3/20 0.46
HPGD P15428 3/20 0.46
HTT P42858 2/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
POLB P06746 1/20 0.45
TSPO P30536 1/20 0.45
HCRTR1 O43613 2/20 0.44
NPC1 O15118 2/20 0.44
ATM Q13315 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
RAB9A P51151 2/20 0.43
KDM4E B2RXH2 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30874765 1.00 PTGER4 (0.50) PTGER4ALDH1A1HPGDHTTMEN1
SCHEMBL2899114 0.92 PTGER4 (0.49) PTGER4ALDH1A1HPGDHTTMEN1
SCHEMBL2801687 0.89 ALDH1A1 (0.56) PTGER4ALDH1A1HPGDPOLBTSPO
SCHEMBL553110 0.87 ALDH1A1 (0.49) PTGER4ALDH1A1HPGDHTTMEN1
SCHEMBL146503 0.87 CYP1A2 (0.56) ALDH1A1HPGDHTTMEN1KMT2A
SCHEMBL24292269 0.86 PTGER4 (0.47) PTGER4ALDH1A1HPGDHTTMEN1
SCHEMBL20990867 0.84 KDM4E (0.47) PTGER4ALDH1A1HPGDHTTMEN1
SCHEMBL9403852 0.83 MAPT (0.55) PTGER4ALDH1A1HPGDHTTMEN1
SCHEMBL604579 0.83 HTT (0.48) PTGER4ALDH1A1HPGDHTTMEN1
SCHEMBL2355430 0.83 ALDH1A1 (0.64) PTGER4ALDH1A1HPGDHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1969027-B1 ARYLAMINE POLYMER CAMBRIDGE DISPLAY TECH LTD (GB) 2013-10-02 EP disclosed
US-8399605-B2 Arylamine polymer CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2013-03-19 US disclosed
US-20080309229-A1 Arylamine Polymer CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2008-12-18 US disclosed
EP-1969027-A1 ARYLAMINE POLYMER Cambridge Display Technology Limited (GB) 2008-09-17 EP disclosed
WO-2007071974-A1 ARYLAMINE POLYMER CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2007-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080309229-A1 Arylamine Polymer NAT1, AR, AHR PTGER4 1442/4885ALDH1A1 627/4885HPGD 4322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.