SCHEMBL2899114

SCHEMBL2899114

C=CCn1c2ccc(-c3ccc4c(c3)c3ccccc3n4C)cc2c2cc(-c3ccc4c(c3)c3ccccc3n4C)ccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 6/20 0.49
GPR3 P46089 1/20 0.47
KDM4E B2RXH2 4/20 0.45
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
L3MBTL1 Q9Y468 3/20 0.45
ALDH1A1 P00352 3/20 0.45
HPGD P15428 3/20 0.45
HTT P42858 3/20 0.45
MAPT P10636 3/20 0.45
HSD17B10 Q99714 2/20 0.45
RXFP1 Q9HBX9 1/20 0.43
TSPO P30536 1/20 0.43
ATM Q13315 2/20 0.43
HCRTR1 O43613 1/20 0.43
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30874765 0.92 PTGER4 (0.50) PTGER4KDM4EMEN1KMT2AL3MBTL1
SCHEMBL4604142 0.92 PTGER4 (0.50) PTGER4KDM4EMEN1KMT2AL3MBTL1
SCHEMBL2801687 0.85 ALDH1A1 (0.56) PTGER4KDM4EL3MBTL1ALDH1A1HPGD
SCHEMBL24292269 0.82 PTGER4 (0.47) PTGER4KDM4EMEN1KMT2AL3MBTL1
SCHEMBL10447275 0.82 GPR3 (0.70) GPR3KDM4EMEN1KMT2AL3MBTL1
SCHEMBL10331500 0.82 GPR3 (0.70) GPR3KDM4EMEN1KMT2AL3MBTL1
SCHEMBL14748530 0.81 KDM4E (0.61) PTGER4GPR3KDM4EMEN1KMT2A
SCHEMBL18213894 0.81 KDM4E (0.61) PTGER4GPR3KDM4EMEN1KMT2A
SCHEMBL553110 0.81 ALDH1A1 (0.49) PTGER4KDM4EMEN1KMT2AL3MBTL1
SCHEMBL17809439 0.81 GPR3 (0.67) GPR3KDM4EMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231814-B1 AN ELECTROCHROMIC COMPOSITION, A METHOD OF FORMING THE ELECTROCHROMIC COMPOSITION AND AN ELECTROCHROMIC APPARATUS DOW CORNING (US) 2014-10-01 EP disclosed
US-8564871-B2 Electrochromic composition, a method of forming the electrochromic composition and an electrochromic apparatus DOW CORNING CORPORATION (US) 2013-10-22 US disclosed
US-20100284053-A1 Electrochromic Composition, A Method Of Forming The Electrochromic Composition And An Electrochromic Apparatus DOW CORNING CORPORATION 2010-11-11 US disclosed
EP-2231814-A1 AN ELECTROCHROMIC COMPOSITION, A METHOD OF FORMING THE ELECTROCHROMIC COMPOSITION AND AN ELECTROCHROMIC APPARATUS Dow Corning Corporation (US) 2010-09-29 EP disclosed
WO-2009089031-A1 AN ELECTROCHROMIC COMPOSITION, A METHOD OF FORMING THE ELECTROCHROMIC COMPOSITION AND AN ELECTROCHROMIC APPARATUS DOW CORNING CORPORATION (US) 2009-07-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100284053-A1 Electrochromic Composition, A Method Of Forming The Electrochromic Composition And An Electrochromic Apparatus ESD, ACHE, EPX PTGER4 3489/4885GPR3 4681/4885KDM4E 971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.