Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 known ✓ | P03956 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 4/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4605228 | 0.97 | STS (0.49) | STSSERPINE1SMN1; SMN2LMNAMAPT | |
| SCHEMBL4605687 | 0.97 | STS (0.49) | STSSERPINE1SMN1; SMN2LMNAMAPT | |
| SCHEMBL178469 | 0.84 | STS (0.51) | STSSERPINE1SMN1; SMN2LMNAMAPT | |
| SCHEMBL6577408 | 0.83 | SERPINE1 (0.60) | STSSERPINE1SMN1; SMN2LMNAMAPT | |
| SCHEMBL27667928 | 0.83 | STS (0.50) | STSSERPINE1SMN1; SMN2LMNAMAPT | |
| SCHEMBL27647401 | 0.83 | STS (0.50) | STSSERPINE1SMN1; SMN2LMNAMAPT | |
| SCHEMBL27667908 | 0.83 | STS (0.50) | STSSERPINE1SMN1; SMN2LMNAMAPT | |
| SCHEMBL27647419 | 0.83 | STS (0.50) | STSSERPINE1SMN1; SMN2LMNAMAPT | |
| SCHEMBL27647426 | 0.83 | STS (0.50) | STSSERPINE1SMN1; SMN2LMNAMAPT | |
| SCHEMBL28761658 | 0.83 | STS (0.50) | STSSERPINE1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139710-B2 | Aliphatic polyester resin compositions, molded articles of aliphatic polyester resin and method of producing same | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 2015-09-22 | — | — | US | disclosed |
| EP-1707598-B1 | ALIPHATIC POLYESTER RESIN COMPOSITION, ALIPHATIC POLYESTER RESIN MOLDING AND PROCESS FOR PRODUCING THE ALIPHATIC POLYESTER RESIN MOLDING | TAKEMOTO OIL & FAT CO LTD (JP) | 2008-07-09 | — | — | EP | disclosed |
| US-20070270535-A1 | Aliphatic Polyester Resin Compositions, Molded Articles of Aliphatic Polyester Resin and Method of Producing Same | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 2007-11-22 | — | — | US | disclosed |
| EP-1707598-A1 | ALIPHATIC POLYESTER RESIN COMPOSITION, ALIPHATIC POLYESTER RESIN MOLDING AND PROCESS FOR PRODUCING THE ALIPHATIC POLYESTER RESIN MOLDING | Takemoto Yushi Kabushiki Kaisha (JP) | 2006-10-04 | — | — | EP | disclosed |