Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4828979 | 0.89 | CXCR2 (0.57) | CXCR2LMNAL3MBTL1PPARGPPARD | |
| SCHEMBL4604550 | 0.87 | CXCR2 (0.59) | CXCR2MAPTALDH1A1LMNARXFP1 | |
| SCHEMBL4606075 | 0.84 | CXCR2 (0.61) | CXCR2MAPTALDH1A1LMNARXFP1 | |
| SCHEMBL4602716 | 0.77 | CXCR2 (0.54) | CXCR2MAPTALDH1A1LMNARXFP1 | |
| SCHEMBL4604985 | 0.77 | CXCR2 (0.54) | CXCR2MAPTLMNAKMT2AL3MBTL1 | |
| SCHEMBL4604246 | 0.76 | CXCR2 (0.53) | CXCR2MAPTALDH1A1LMNARXFP1 | |
| SCHEMBL4633571 | 0.75 | CXCR2 (0.55) | CXCR2MAPTALDH1A1LMNARXFP1 | |
| SCHEMBL4606183 | 0.75 | CXCR2 (0.48) | CXCR2MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL4605238 | 0.75 | CXCR2 (0.52) | CXCR2MAPTALDH1A1LMNARXFP1 | |
| SCHEMBL4633030 | 0.74 | CXCR2 (0.52) | CXCR2LMNAL3MBTL1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685122-B1 | BENZOFURANS AND BENZOTHIOPHENES | MERCK PATENT GMBH (DE) | 2008-07-09 | — | — | EP | disclosed |